The role of capsule endoscopy after negative CT enterography in patients with obscure gastrointestinal bleeding

Hyun Mi Heo, Chan Hyuk Park, Joon Seok Lim, Jin Ha Lee, Bo Kyung Kim, Jae Hee Cheon, Tae Il Kim, Won Ho Kim, Sung Pil Hong

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objectives The aim of the present study was to evaluate the role of capsule endoscopy in patients with obscure gastrointestinal bleeding (OGIB) after negative computed tomographic (CT) enterography. Methods We retrospectively included 30 patients with OGIB who received capsule endoscopy after negative CT enterography. The median age of the patients was 60 years, and 60% of patients were male. The median follow-up duration was 8 months. Overt bleeding was 60%, and occult bleeding was 40%. Results Based on capsule endoscopy results, a definitive diagnosis was made for 17 patients (57%): ulcer in nine patients (30%), active bleeding with no identifiable cause in five (17%), angiodysplasia in two (7%) and Dieulafoy's lesion in one (3%). Two patients with jejunal ulcers were diagnosed with Crohn's disease. Seven patients (41%) with positive capsule endoscopy received double balloon enteroscopy and two patients (12%) received steroid treatment for Crohn's disease. Patients with overt bleeding, a previous history of bleeding, or who received large amounts of blood transfusions were more likely to show positive capsule endoscopy. Conclusions Capsule endoscopy showed high diagnostic yields in patients with OGIB after negative CT enterography and may help to provide further therapeutic plans for patients with OGIB and negative CT enterography. Key Points • CT enterography has been widely used in evaluating obscure gastrointestinal bleeding (OGIB). • Capsule endoscopy showed high diagnostic yield for OGIB after negative CT enterography. • Negative CT enterography does not exclude important causes of small bowel bleeding. • Most lesions missed at CT-enterography are flat and can be detected by capsule endoscopy.

Original languageEnglish
Pages (from-to)1159-1166
Number of pages8
JournalEuropean Radiology
Volume22
Issue number6
DOIs
Publication statusPublished - 2012 Jun 1

Fingerprint

Capsule Endoscopy
Hemorrhage
Crohn Disease
Ulcer
Double-Balloon Enteroscopy
Angiodysplasia
Blood Transfusion

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Heo, Hyun Mi ; Park, Chan Hyuk ; Lim, Joon Seok ; Lee, Jin Ha ; Kim, Bo Kyung ; Cheon, Jae Hee ; Kim, Tae Il ; Kim, Won Ho ; Hong, Sung Pil. / The role of capsule endoscopy after negative CT enterography in patients with obscure gastrointestinal bleeding. In: European Radiology. 2012 ; Vol. 22, No. 6. pp. 1159-1166.
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abstract = "Objectives The aim of the present study was to evaluate the role of capsule endoscopy in patients with obscure gastrointestinal bleeding (OGIB) after negative computed tomographic (CT) enterography. Methods We retrospectively included 30 patients with OGIB who received capsule endoscopy after negative CT enterography. The median age of the patients was 60 years, and 60{\%} of patients were male. The median follow-up duration was 8 months. Overt bleeding was 60{\%}, and occult bleeding was 40{\%}. Results Based on capsule endoscopy results, a definitive diagnosis was made for 17 patients (57{\%}): ulcer in nine patients (30{\%}), active bleeding with no identifiable cause in five (17{\%}), angiodysplasia in two (7{\%}) and Dieulafoy's lesion in one (3{\%}). Two patients with jejunal ulcers were diagnosed with Crohn's disease. Seven patients (41{\%}) with positive capsule endoscopy received double balloon enteroscopy and two patients (12{\%}) received steroid treatment for Crohn's disease. Patients with overt bleeding, a previous history of bleeding, or who received large amounts of blood transfusions were more likely to show positive capsule endoscopy. Conclusions Capsule endoscopy showed high diagnostic yields in patients with OGIB after negative CT enterography and may help to provide further therapeutic plans for patients with OGIB and negative CT enterography. Key Points • CT enterography has been widely used in evaluating obscure gastrointestinal bleeding (OGIB). • Capsule endoscopy showed high diagnostic yield for OGIB after negative CT enterography. • Negative CT enterography does not exclude important causes of small bowel bleeding. • Most lesions missed at CT-enterography are flat and can be detected by capsule endoscopy.",
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The role of capsule endoscopy after negative CT enterography in patients with obscure gastrointestinal bleeding. / Heo, Hyun Mi; Park, Chan Hyuk; Lim, Joon Seok; Lee, Jin Ha; Kim, Bo Kyung; Cheon, Jae Hee; Kim, Tae Il; Kim, Won Ho; Hong, Sung Pil.

In: European Radiology, Vol. 22, No. 6, 01.06.2012, p. 1159-1166.

Research output: Contribution to journalArticle

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AU - Heo, Hyun Mi

AU - Park, Chan Hyuk

AU - Lim, Joon Seok

AU - Lee, Jin Ha

AU - Kim, Bo Kyung

AU - Cheon, Jae Hee

AU - Kim, Tae Il

AU - Kim, Won Ho

AU - Hong, Sung Pil

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N2 - Objectives The aim of the present study was to evaluate the role of capsule endoscopy in patients with obscure gastrointestinal bleeding (OGIB) after negative computed tomographic (CT) enterography. Methods We retrospectively included 30 patients with OGIB who received capsule endoscopy after negative CT enterography. The median age of the patients was 60 years, and 60% of patients were male. The median follow-up duration was 8 months. Overt bleeding was 60%, and occult bleeding was 40%. Results Based on capsule endoscopy results, a definitive diagnosis was made for 17 patients (57%): ulcer in nine patients (30%), active bleeding with no identifiable cause in five (17%), angiodysplasia in two (7%) and Dieulafoy's lesion in one (3%). Two patients with jejunal ulcers were diagnosed with Crohn's disease. Seven patients (41%) with positive capsule endoscopy received double balloon enteroscopy and two patients (12%) received steroid treatment for Crohn's disease. Patients with overt bleeding, a previous history of bleeding, or who received large amounts of blood transfusions were more likely to show positive capsule endoscopy. Conclusions Capsule endoscopy showed high diagnostic yields in patients with OGIB after negative CT enterography and may help to provide further therapeutic plans for patients with OGIB and negative CT enterography. Key Points • CT enterography has been widely used in evaluating obscure gastrointestinal bleeding (OGIB). • Capsule endoscopy showed high diagnostic yield for OGIB after negative CT enterography. • Negative CT enterography does not exclude important causes of small bowel bleeding. • Most lesions missed at CT-enterography are flat and can be detected by capsule endoscopy.

AB - Objectives The aim of the present study was to evaluate the role of capsule endoscopy in patients with obscure gastrointestinal bleeding (OGIB) after negative computed tomographic (CT) enterography. Methods We retrospectively included 30 patients with OGIB who received capsule endoscopy after negative CT enterography. The median age of the patients was 60 years, and 60% of patients were male. The median follow-up duration was 8 months. Overt bleeding was 60%, and occult bleeding was 40%. Results Based on capsule endoscopy results, a definitive diagnosis was made for 17 patients (57%): ulcer in nine patients (30%), active bleeding with no identifiable cause in five (17%), angiodysplasia in two (7%) and Dieulafoy's lesion in one (3%). Two patients with jejunal ulcers were diagnosed with Crohn's disease. Seven patients (41%) with positive capsule endoscopy received double balloon enteroscopy and two patients (12%) received steroid treatment for Crohn's disease. Patients with overt bleeding, a previous history of bleeding, or who received large amounts of blood transfusions were more likely to show positive capsule endoscopy. Conclusions Capsule endoscopy showed high diagnostic yields in patients with OGIB after negative CT enterography and may help to provide further therapeutic plans for patients with OGIB and negative CT enterography. Key Points • CT enterography has been widely used in evaluating obscure gastrointestinal bleeding (OGIB). • Capsule endoscopy showed high diagnostic yield for OGIB after negative CT enterography. • Negative CT enterography does not exclude important causes of small bowel bleeding. • Most lesions missed at CT-enterography are flat and can be detected by capsule endoscopy.

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