Objective Head and neck tumors are a heterogeneous group and often invade the skull base. Various radiation techniques can be used for these tumors when surgery is unavailable. This study investigated the indications for gamma knife radiosurgery (GKRS) in benign head and neck tumors. Methods Thirty-seven lesions in 35 patients were treated with GKRS for schwannoma, juvenile nasal angiofibroma, choroidal hemangioma, and pleomorphic adenoma. The median follow-up period was 43.0 months (range, 12.2-174.1 months). Results Tumor control was achieved in 35 of 37 lesions (94.6%) at last follow-up after GKRS. Thirty-four lesions (91.9%) decreased, 1 lesion (2.7%) remained stable, and 2 lesions (5.4%) increased in size. Clinically, 15 cases (40.5%) showed improvement, 17 cases (45.9%) were stable, 1 case (2.7%) experienced deterioration, and 4 cases (10.8%) developed new symptoms. Four of the 5 cases that exhibited deterioration or new symptoms improved. Conclusions GKRS is a reasonable alternative to surgery that can effectively control tumor growth and preserve functions of the head and neck in primary, residual, or recurrent benign head and neck tumors.
Bibliographical noteFunding Information:
This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministery of Education, Science and Technology (NRF-2014R1A1A2058058).
Conflict of interest statement: This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( NRF-2014R1A1A2058058 ).
© 2016 Elsevier Inc.
All Science Journal Classification (ASJC) codes
- Clinical Neurology