The surgical effect of callosotomy in the treatment of intractable seizure

Dong Seok Kim, Kook Hee Yang, Tae Gon Kim, Jong Hee Chang, Jin Woo Chang, Joong Uhn Choi, Byung In Lee

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalYonsei medical journal
Volume45
Issue number2
DOIs
Publication statusPublished - 2004 Apr 30

Fingerprint

Seizures
Syncope
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, D. S., Yang, K. H., Kim, T. G., Chang, J. H., Chang, J. W., Choi, J. U., & Lee, B. I. (2004). The surgical effect of callosotomy in the treatment of intractable seizure. Yonsei medical journal, 45(2), 233-240. https://doi.org/10.3349/ymj.2004.45.2.233
Kim, Dong Seok ; Yang, Kook Hee ; Kim, Tae Gon ; Chang, Jong Hee ; Chang, Jin Woo ; Choi, Joong Uhn ; Lee, Byung In. / The surgical effect of callosotomy in the treatment of intractable seizure. In: Yonsei medical journal. 2004 ; Vol. 45, No. 2. pp. 233-240.
@article{768fe5611a6746d9b9665666640c1d2c,
title = "The surgical effect of callosotomy in the treatment of intractable seizure",
abstract = "We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75{\%} in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.",
author = "Kim, {Dong Seok} and Yang, {Kook Hee} and Kim, {Tae Gon} and Chang, {Jong Hee} and Chang, {Jin Woo} and Choi, {Joong Uhn} and Lee, {Byung In}",
year = "2004",
month = "4",
day = "30",
doi = "10.3349/ymj.2004.45.2.233",
language = "English",
volume = "45",
pages = "233--240",
journal = "Yonsei Medical Journal",
issn = "0513-5796",
publisher = "Yonsei University College of Medicine",
number = "2",

}

Kim, DS, Yang, KH, Kim, TG, Chang, JH, Chang, JW, Choi, JU & Lee, BI 2004, 'The surgical effect of callosotomy in the treatment of intractable seizure', Yonsei medical journal, vol. 45, no. 2, pp. 233-240. https://doi.org/10.3349/ymj.2004.45.2.233

The surgical effect of callosotomy in the treatment of intractable seizure. / Kim, Dong Seok; Yang, Kook Hee; Kim, Tae Gon; Chang, Jong Hee; Chang, Jin Woo; Choi, Joong Uhn; Lee, Byung In.

In: Yonsei medical journal, Vol. 45, No. 2, 30.04.2004, p. 233-240.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The surgical effect of callosotomy in the treatment of intractable seizure

AU - Kim, Dong Seok

AU - Yang, Kook Hee

AU - Kim, Tae Gon

AU - Chang, Jong Hee

AU - Chang, Jin Woo

AU - Choi, Joong Uhn

AU - Lee, Byung In

PY - 2004/4/30

Y1 - 2004/4/30

N2 - We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.

AB - We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.

UR - http://www.scopus.com/inward/record.url?scp=2442698839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2442698839&partnerID=8YFLogxK

U2 - 10.3349/ymj.2004.45.2.233

DO - 10.3349/ymj.2004.45.2.233

M3 - Article

C2 - 15118994

AN - SCOPUS:2442698839

VL - 45

SP - 233

EP - 240

JO - Yonsei Medical Journal

JF - Yonsei Medical Journal

SN - 0513-5796

IS - 2

ER -