The surgical effect of callosotomy in the treatment of intractable seizure

Dong Seok Kim, Kook Hee Yang, Tae Gon Kim, Jong Hee Chang, Jin Woo Chang, Joong Uhn Choi, Byung In Lee

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalYonsei medical journal
Volume45
Issue number2
DOIs
Publication statusPublished - 2004 Apr 30

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Kim, D. S., Yang, K. H., Kim, T. G., Chang, J. H., Chang, J. W., Choi, J. U., & Lee, B. I. (2004). The surgical effect of callosotomy in the treatment of intractable seizure. Yonsei medical journal, 45(2), 233-240. https://doi.org/10.3349/ymj.2004.45.2.233