TY - GEN
T1 - Three dimensional electrode structure controlled by dielectrophoresis for flow-through micro electroporation system
AU - Choi, Youn Suk
AU - Kim, Young Ji
AU - Im, Maesoon
AU - Kim, Byoung Gyun
AU - Yun, Kwang Seok
AU - Yoon, Euisik
PY - 2006
Y1 - 2006
N2 - A three dimensional electrode structure for flow-through micro electroporation is proposed to achieve well-controlled cell positioning in a confined region. In this structure, cell position is actively performed by using dielectrophoresis in a three dimensional electrode structure. Compared with conventional planar electrode structures, the proposed electrode structure can achieve excellent aligning of cells not only in horizontal dimension but also in vertical dimension for receiving uniform electrical field during electroporation. The effectiveness of the proposed structure is validated by both numerical simulation using a commercial tool, CFD-ACE+, and experiments using the fabricated microfluidic chip. The results are compared with conventional parallel finger electrode structures under the same conditions.
AB - A three dimensional electrode structure for flow-through micro electroporation is proposed to achieve well-controlled cell positioning in a confined region. In this structure, cell position is actively performed by using dielectrophoresis in a three dimensional electrode structure. Compared with conventional planar electrode structures, the proposed electrode structure can achieve excellent aligning of cells not only in horizontal dimension but also in vertical dimension for receiving uniform electrical field during electroporation. The effectiveness of the proposed structure is validated by both numerical simulation using a commercial tool, CFD-ACE+, and experiments using the fabricated microfluidic chip. The results are compared with conventional parallel finger electrode structures under the same conditions.
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M3 - Conference contribution
AN - SCOPUS:33750129202
SN - 0780394755
SN - 9780780394759
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 466
EP - 469
BT - 19th IEEE International Conference on Micro Electro Mechanical Systems
T2 - 19th IEEE International Conference on Micro Electro Mechanical Systems
Y2 - 22 January 2006 through 26 January 2006
ER -