Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles

Kwanghun Chung, Jaekyu Cho, Lauren Cheplen, Victor Breedveld, Hang Lu

Research output: Contribution to conferencePaper

Abstract

We report an in situ method for temperature measurement in microfluidic systems using Brownian diffussion of nanoparticles. This method is superior in its reproducibility and reduced systematic errors as measuring Brownian diffusivity does not rely on fluorescence intensity or lifetime of fluorophores. Threedimensional temperature mapping was achieved using a simple videomicroscopy setup in combination with software analysis that enables selective tracking of nanoparticles. In addition, we successfully demonstrated the capability of this method as an in situ noninvasive temperature measurement tool for biological samples.

Original languageEnglish
Pages646-648
Number of pages3
Publication statusPublished - 2008 Jan 1
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 2008 Oct 122008 Oct 16

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period08/10/1208/10/16

Fingerprint

Brownian movement
Microfluidics
Temperature measurement
Nanoparticles
Fluorophores
Systematic errors
Fluorescence
Temperature

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Chung, K., Cho, J., Cheplen, L., Breedveld, V., & Lu, H. (2008). Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles. 646-648. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.
Chung, Kwanghun ; Cho, Jaekyu ; Cheplen, Lauren ; Breedveld, Victor ; Lu, Hang. / Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.3 p.
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Chung, K, Cho, J, Cheplen, L, Breedveld, V & Lu, H 2008, 'Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles' Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States, 08/10/12 - 08/10/16, pp. 646-648.

Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles. / Chung, Kwanghun; Cho, Jaekyu; Cheplen, Lauren; Breedveld, Victor; Lu, Hang.

2008. 646-648 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conferencePaper

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Chung K, Cho J, Cheplen L, Breedveld V, Lu H. Three-dimensional in situ temperature measurement in microfluidic system using brownian motion of nanoparticles. 2008. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.