Three-pool model vs. nonnegative least squares algorithm for myelin water quantification

Hyunjin Chung, Yoonho Nam, Donghyun Kim, Dosik Hwang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, comparison of two T2 based analysis technique for measurements of myelin content, regularized non-negative least squares (rNNLS) algorithm and three-pool modeling method, have been presented. Simulation and in vivo experiments were performed for the comparison of the two techniques. For fair comparison, both discretely and continuously distributed T2 spectrum were considered in the simulations. The simulation and in vivo experiments have been demonstrated that three-pool model is more appropriate method for robust myelin water quantification.

Original languageEnglish
Title of host publication54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011
DOIs
Publication statusPublished - 2011 Oct 13
Event54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011 - Seoul, Korea, Republic of
Duration: 2011 Aug 72011 Aug 10

Publication series

NameMidwest Symposium on Circuits and Systems
ISSN (Print)1548-3746

Other

Other54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011
CountryKorea, Republic of
CitySeoul
Period11/8/711/8/10

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All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

Cite this

Chung, H., Nam, Y., Kim, D., & Hwang, D. (2011). Three-pool model vs. nonnegative least squares algorithm for myelin water quantification. In 54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011 [6026476] (Midwest Symposium on Circuits and Systems). https://doi.org/10.1109/MWSCAS.2011.6026476