TY - GEN
T1 - Three-pool model vs. nonnegative least squares algorithm for myelin water quantification
AU - Chung, Hyunjin
AU - Nam, Yoonho
AU - Kim, Donghyun
AU - Hwang, Dosik
PY - 2011
Y1 - 2011
N2 - In this paper, comparison of two T2 based analysis technique for measurements of myelin content, regularized non-negative least squares (rNNLS) algorithm and three-pool modeling method, have been presented. Simulation and in vivo experiments were performed for the comparison of the two techniques. For fair comparison, both discretely and continuously distributed T2 spectrum were considered in the simulations. The simulation and in vivo experiments have been demonstrated that three-pool model is more appropriate method for robust myelin water quantification.
AB - In this paper, comparison of two T2 based analysis technique for measurements of myelin content, regularized non-negative least squares (rNNLS) algorithm and three-pool modeling method, have been presented. Simulation and in vivo experiments were performed for the comparison of the two techniques. For fair comparison, both discretely and continuously distributed T2 spectrum were considered in the simulations. The simulation and in vivo experiments have been demonstrated that three-pool model is more appropriate method for robust myelin water quantification.
UR - http://www.scopus.com/inward/record.url?scp=80053639324&partnerID=8YFLogxK
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U2 - 10.1109/MWSCAS.2011.6026476
DO - 10.1109/MWSCAS.2011.6026476
M3 - Conference contribution
AN - SCOPUS:80053639324
SN - 9781612848570
T3 - Midwest Symposium on Circuits and Systems
BT - 54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011
T2 - 54th IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2011
Y2 - 7 August 2011 through 10 August 2011
ER -