Topographic relationship between the supratrochlear nerve and corrugator supercilii muscle—Can this anatomical knowledge improve the response to botulinum toxin injections in chronic migraine?

Hyung Jin Lee, Kwang Seok Choi, Sung Yoon Won, Prawit Apinuntrum, Kyung Seok Hu, Seong Taek Kim, Tanvaa Tansatit, Hee Jin Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Chronic migraine has been related to the entrapment of the supratrochlear nerve within the corrugator supercilii muscle. Recently, research has shown that people who have undergone botulinum neurotoxin A injection in frontal regions reported disappearance or alleviation of their migraines. There have been numerous anatomical studies conducted on Caucasians revealing possible anatomical problems leading to migraine; on the other hand, relatively few anatomical studies have been conducted on Asians. Thus, the aim of the present study was to determine the topographic relationship between the supratrochlear nerve and corrugator supercilii muscle in the forehead that may be the cause of migraine. Fifty-eight hemifaces from Korean and Thai cadavers were used for this study. The supratrochlear nerve entered the corrugator supercilii muscle in every case. Type I, in which the supratrochlear nerve emerged separately from the supraorbital nerve at the medial one-third portion of the orbit, was observed in 69% (40/58) of cases. Type II, in which the supratrochlear nerve emerged from the orbit at the same location as the supraorbital nerve, was observed in 31% (18/58) of cases.

Original languageEnglish
Pages (from-to)2629-2638
Number of pages10
JournalToxins
Volume7
Issue number7
DOIs
Publication statusPublished - 2015 Jul 17

Fingerprint

Botulinum Toxins
Migraine Disorders
Muscle
Injections
Orbits
Orbit
Muscles
Type A Botulinum Toxins
Nerve Compression Syndromes
Forehead
Cadaver
Research

All Science Journal Classification (ASJC) codes

  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

Lee, Hyung Jin ; Choi, Kwang Seok ; Won, Sung Yoon ; Apinuntrum, Prawit ; Hu, Kyung Seok ; Kim, Seong Taek ; Tansatit, Tanvaa ; Kim, Hee Jin. / Topographic relationship between the supratrochlear nerve and corrugator supercilii muscle—Can this anatomical knowledge improve the response to botulinum toxin injections in chronic migraine?. In: Toxins. 2015 ; Vol. 7, No. 7. pp. 2629-2638.
@article{2754372cfed94c6188d0920f3fb57552,
title = "Topographic relationship between the supratrochlear nerve and corrugator supercilii muscle—Can this anatomical knowledge improve the response to botulinum toxin injections in chronic migraine?",
abstract = "Chronic migraine has been related to the entrapment of the supratrochlear nerve within the corrugator supercilii muscle. Recently, research has shown that people who have undergone botulinum neurotoxin A injection in frontal regions reported disappearance or alleviation of their migraines. There have been numerous anatomical studies conducted on Caucasians revealing possible anatomical problems leading to migraine; on the other hand, relatively few anatomical studies have been conducted on Asians. Thus, the aim of the present study was to determine the topographic relationship between the supratrochlear nerve and corrugator supercilii muscle in the forehead that may be the cause of migraine. Fifty-eight hemifaces from Korean and Thai cadavers were used for this study. The supratrochlear nerve entered the corrugator supercilii muscle in every case. Type I, in which the supratrochlear nerve emerged separately from the supraorbital nerve at the medial one-third portion of the orbit, was observed in 69{\%} (40/58) of cases. Type II, in which the supratrochlear nerve emerged from the orbit at the same location as the supraorbital nerve, was observed in 31{\%} (18/58) of cases.",
author = "Lee, {Hyung Jin} and Choi, {Kwang Seok} and Won, {Sung Yoon} and Prawit Apinuntrum and Hu, {Kyung Seok} and Kim, {Seong Taek} and Tanvaa Tansatit and Kim, {Hee Jin}",
year = "2015",
month = "7",
day = "17",
doi = "10.3390/toxins7072629",
language = "English",
volume = "7",
pages = "2629--2638",
journal = "Toxins",
issn = "2072-6651",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "7",

}

Topographic relationship between the supratrochlear nerve and corrugator supercilii muscle—Can this anatomical knowledge improve the response to botulinum toxin injections in chronic migraine? / Lee, Hyung Jin; Choi, Kwang Seok; Won, Sung Yoon; Apinuntrum, Prawit; Hu, Kyung Seok; Kim, Seong Taek; Tansatit, Tanvaa; Kim, Hee Jin.

In: Toxins, Vol. 7, No. 7, 17.07.2015, p. 2629-2638.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Topographic relationship between the supratrochlear nerve and corrugator supercilii muscle—Can this anatomical knowledge improve the response to botulinum toxin injections in chronic migraine?

AU - Lee, Hyung Jin

AU - Choi, Kwang Seok

AU - Won, Sung Yoon

AU - Apinuntrum, Prawit

AU - Hu, Kyung Seok

AU - Kim, Seong Taek

AU - Tansatit, Tanvaa

AU - Kim, Hee Jin

PY - 2015/7/17

Y1 - 2015/7/17

N2 - Chronic migraine has been related to the entrapment of the supratrochlear nerve within the corrugator supercilii muscle. Recently, research has shown that people who have undergone botulinum neurotoxin A injection in frontal regions reported disappearance or alleviation of their migraines. There have been numerous anatomical studies conducted on Caucasians revealing possible anatomical problems leading to migraine; on the other hand, relatively few anatomical studies have been conducted on Asians. Thus, the aim of the present study was to determine the topographic relationship between the supratrochlear nerve and corrugator supercilii muscle in the forehead that may be the cause of migraine. Fifty-eight hemifaces from Korean and Thai cadavers were used for this study. The supratrochlear nerve entered the corrugator supercilii muscle in every case. Type I, in which the supratrochlear nerve emerged separately from the supraorbital nerve at the medial one-third portion of the orbit, was observed in 69% (40/58) of cases. Type II, in which the supratrochlear nerve emerged from the orbit at the same location as the supraorbital nerve, was observed in 31% (18/58) of cases.

AB - Chronic migraine has been related to the entrapment of the supratrochlear nerve within the corrugator supercilii muscle. Recently, research has shown that people who have undergone botulinum neurotoxin A injection in frontal regions reported disappearance or alleviation of their migraines. There have been numerous anatomical studies conducted on Caucasians revealing possible anatomical problems leading to migraine; on the other hand, relatively few anatomical studies have been conducted on Asians. Thus, the aim of the present study was to determine the topographic relationship between the supratrochlear nerve and corrugator supercilii muscle in the forehead that may be the cause of migraine. Fifty-eight hemifaces from Korean and Thai cadavers were used for this study. The supratrochlear nerve entered the corrugator supercilii muscle in every case. Type I, in which the supratrochlear nerve emerged separately from the supraorbital nerve at the medial one-third portion of the orbit, was observed in 69% (40/58) of cases. Type II, in which the supratrochlear nerve emerged from the orbit at the same location as the supraorbital nerve, was observed in 31% (18/58) of cases.

UR - http://www.scopus.com/inward/record.url?scp=84941919767&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941919767&partnerID=8YFLogxK

U2 - 10.3390/toxins7072629

DO - 10.3390/toxins7072629

M3 - Article

C2 - 26193317

AN - SCOPUS:84941919767

VL - 7

SP - 2629

EP - 2638

JO - Toxins

JF - Toxins

SN - 2072-6651

IS - 7

ER -