The first asymmetric total syntheses of urgineanins A, B, and D - potent antiproliferative homoisoflavonoids - were achieved by utilizing Pd-catalyzed allylic substitution of the allylic acetate with arylboronic acids for introduction of the C rings of homoisoflavonoid skeleton. Several unnatural urgineanin analogues were also prepared in this manner.
|Number of pages||7|
|Publication status||Published - 2017 Apr 1|
Bibliographical noteFunding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP(2014R1A2A1A11050491). This work was supported in part by the Yonsei Research Fund of 2015 (project no.: 2015-12-0215).
© Georg Thieme VerlagStuttgart · New York.
All Science Journal Classification (ASJC) codes
- Organic Chemistry