Total Syntheses of Urgineanins A, B, D, and Their Analogues

Dileep Kumar Singh, Youngeun Jung, Ikyon Kim

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The first asymmetric total syntheses of urgineanins A, B, and D - potent antiproliferative homoisoflavonoids - were achieved by utilizing Pd-catalyzed allylic substitution of the allylic acetate with arylboronic acids for introduction of the C rings of homoisoflavonoid skeleton. Several unnatural urgineanin analogues were also prepared in this manner.

Original languageEnglish
Article numberss-2016-h0625-op
Pages (from-to)1531-1537
Number of pages7
JournalSynthesis (Germany)
Volume49
Issue number7
DOIs
Publication statusPublished - 2017 Apr 1

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP(2014R1A2A1A11050491). This work was supported in part by the Yonsei Research Fund of 2015 (project no.: 2015-12-0215).

Publisher Copyright:
© Georg Thieme VerlagStuttgart · New York.

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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