Towards integrated optical chromatography using photonic crystal fiber

P. C. Ashok, R. F. Marchington, M. Mazilu, T. F. Krauss, K. Dholakia

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical chromatography is a powerful technique, capable of separating micron-sized particles within a fluid flow, based on their intrinsic properties, including size, shape and refractive index. Briefly, particles in a fluid flow are subject to two forces, the Stokes drag force due to the fluid and then an introduced optical force as supplied by a laser beam, acting in opposite but collinear directions. According to the particle's intrinsic hydrodynamic and optical properties, equilibrium positions may form where the two forces balance, which is highly dependent on the properties of the particle and as a result provides a means for spatial separation in a sample mixture. Optical chromatography is a passive sorting technique, where pre-tagging of the particles of interest is not required, allowing for non-discrete distributions to be evaluated and/or separated. Firstly we review the current stage of optical chromatography. We present a new advance in optical chromatography potentially enabling the unique beam delivery properties of photonic crystal fiber (PCF) to be employed and integrated into microfluidic chips. Also, for the first time a finite element method is applied to the optical field in the theoretical analysis of optical chromatography, which is found to be in excellent agreement with the current ray optics model, even for particles much smaller than the optical wavelength. This will pave the way for the technique to be extended into the nanoparticle regime.

Original languageEnglish
Title of host publicationOptical Trapping and Optical Micromanipulation VI
DOIs
Publication statusPublished - 2009 Nov 23
EventOptical Trapping and Optical Micromanipulation VI - San Diego, CA, United States
Duration: 2009 Aug 22009 Aug 6

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7400
ISSN (Print)0277-786X

Conference

ConferenceOptical Trapping and Optical Micromanipulation VI
CountryUnited States
CitySan Diego, CA
Period09/8/209/8/6

Fingerprint

Photonic crystal fibers
chromatography
Chromatography
Photonic Crystal
Fiber
photonics
fibers
crystals
Flow of fluids
fluid flow
Fluid Flow
Optical Forces
Sorting
Microfluidics
geometrical optics
Laser beams
Drag
Drag Force
Optics
classifying

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Ashok, P. C., Marchington, R. F., Mazilu, M., Krauss, T. F., & Dholakia, K. (2009). Towards integrated optical chromatography using photonic crystal fiber. In Optical Trapping and Optical Micromanipulation VI [74000R] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 7400). https://doi.org/10.1117/12.825933
Ashok, P. C. ; Marchington, R. F. ; Mazilu, M. ; Krauss, T. F. ; Dholakia, K. / Towards integrated optical chromatography using photonic crystal fiber. Optical Trapping and Optical Micromanipulation VI. 2009. (Proceedings of SPIE - The International Society for Optical Engineering).
@inproceedings{5bbc47786c93482c8cadf8543bb04433,
title = "Towards integrated optical chromatography using photonic crystal fiber",
abstract = "Optical chromatography is a powerful technique, capable of separating micron-sized particles within a fluid flow, based on their intrinsic properties, including size, shape and refractive index. Briefly, particles in a fluid flow are subject to two forces, the Stokes drag force due to the fluid and then an introduced optical force as supplied by a laser beam, acting in opposite but collinear directions. According to the particle's intrinsic hydrodynamic and optical properties, equilibrium positions may form where the two forces balance, which is highly dependent on the properties of the particle and as a result provides a means for spatial separation in a sample mixture. Optical chromatography is a passive sorting technique, where pre-tagging of the particles of interest is not required, allowing for non-discrete distributions to be evaluated and/or separated. Firstly we review the current stage of optical chromatography. We present a new advance in optical chromatography potentially enabling the unique beam delivery properties of photonic crystal fiber (PCF) to be employed and integrated into microfluidic chips. Also, for the first time a finite element method is applied to the optical field in the theoretical analysis of optical chromatography, which is found to be in excellent agreement with the current ray optics model, even for particles much smaller than the optical wavelength. This will pave the way for the technique to be extended into the nanoparticle regime.",
author = "Ashok, {P. C.} and Marchington, {R. F.} and M. Mazilu and Krauss, {T. F.} and K. Dholakia",
year = "2009",
month = "11",
day = "23",
doi = "10.1117/12.825933",
language = "English",
isbn = "9780819476906",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
booktitle = "Optical Trapping and Optical Micromanipulation VI",

}

Ashok, PC, Marchington, RF, Mazilu, M, Krauss, TF & Dholakia, K 2009, Towards integrated optical chromatography using photonic crystal fiber. in Optical Trapping and Optical Micromanipulation VI., 74000R, Proceedings of SPIE - The International Society for Optical Engineering, vol. 7400, Optical Trapping and Optical Micromanipulation VI, San Diego, CA, United States, 09/8/2. https://doi.org/10.1117/12.825933

Towards integrated optical chromatography using photonic crystal fiber. / Ashok, P. C.; Marchington, R. F.; Mazilu, M.; Krauss, T. F.; Dholakia, K.

Optical Trapping and Optical Micromanipulation VI. 2009. 74000R (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 7400).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Towards integrated optical chromatography using photonic crystal fiber

AU - Ashok, P. C.

AU - Marchington, R. F.

AU - Mazilu, M.

AU - Krauss, T. F.

AU - Dholakia, K.

PY - 2009/11/23

Y1 - 2009/11/23

N2 - Optical chromatography is a powerful technique, capable of separating micron-sized particles within a fluid flow, based on their intrinsic properties, including size, shape and refractive index. Briefly, particles in a fluid flow are subject to two forces, the Stokes drag force due to the fluid and then an introduced optical force as supplied by a laser beam, acting in opposite but collinear directions. According to the particle's intrinsic hydrodynamic and optical properties, equilibrium positions may form where the two forces balance, which is highly dependent on the properties of the particle and as a result provides a means for spatial separation in a sample mixture. Optical chromatography is a passive sorting technique, where pre-tagging of the particles of interest is not required, allowing for non-discrete distributions to be evaluated and/or separated. Firstly we review the current stage of optical chromatography. We present a new advance in optical chromatography potentially enabling the unique beam delivery properties of photonic crystal fiber (PCF) to be employed and integrated into microfluidic chips. Also, for the first time a finite element method is applied to the optical field in the theoretical analysis of optical chromatography, which is found to be in excellent agreement with the current ray optics model, even for particles much smaller than the optical wavelength. This will pave the way for the technique to be extended into the nanoparticle regime.

AB - Optical chromatography is a powerful technique, capable of separating micron-sized particles within a fluid flow, based on their intrinsic properties, including size, shape and refractive index. Briefly, particles in a fluid flow are subject to two forces, the Stokes drag force due to the fluid and then an introduced optical force as supplied by a laser beam, acting in opposite but collinear directions. According to the particle's intrinsic hydrodynamic and optical properties, equilibrium positions may form where the two forces balance, which is highly dependent on the properties of the particle and as a result provides a means for spatial separation in a sample mixture. Optical chromatography is a passive sorting technique, where pre-tagging of the particles of interest is not required, allowing for non-discrete distributions to be evaluated and/or separated. Firstly we review the current stage of optical chromatography. We present a new advance in optical chromatography potentially enabling the unique beam delivery properties of photonic crystal fiber (PCF) to be employed and integrated into microfluidic chips. Also, for the first time a finite element method is applied to the optical field in the theoretical analysis of optical chromatography, which is found to be in excellent agreement with the current ray optics model, even for particles much smaller than the optical wavelength. This will pave the way for the technique to be extended into the nanoparticle regime.

UR - http://www.scopus.com/inward/record.url?scp=70449640287&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70449640287&partnerID=8YFLogxK

U2 - 10.1117/12.825933

DO - 10.1117/12.825933

M3 - Conference contribution

AN - SCOPUS:70449640287

SN - 9780819476906

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Optical Trapping and Optical Micromanipulation VI

ER -

Ashok PC, Marchington RF, Mazilu M, Krauss TF, Dholakia K. Towards integrated optical chromatography using photonic crystal fiber. In Optical Trapping and Optical Micromanipulation VI. 2009. 74000R. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.825933