Transport disc distraction osteogenesis for the reconstruction of a calvarial defect

Jong Won Hong, Seung Yong Song, Dae Gon Woo, Han Sung Kim, Hyun Joon Hong, Joong Ho Choi, Beyoung Yun Park, Yong Oock Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

PURPOSE: Reconstruction of bone defects is possible through distraction osteogenesis using small bone transport discs. The aim of this study was to evaluate the usability of transport disc distraction osteogenesis (TDDO) in the reconstruction of skull defects in an animal experiment. METHODS: Eleven mongrel female dogs were used. Craniectomy (33 × 15 mm) was performed on both sides of the parietal bone symmetrically. On the experimental site, the 7 × 15-mm transport bone disc was used for TDDO. The control site was left in the defect state. An external distraction device was used. The latency period was 5 days, the rate of distraction was 1 mm/d, and distraction was done for 26 days. After a 6-month consolidation period, a computed tomographic scan was performed. The area of regenerated bone was measured from the computed tomographic scan. The hardness was checked on the regenerated bone and the normal bone. A histologic examination of the regenerated bone was done. RESULT: Eight cases were included in the evaluation, and 3 cases were excluded because they showed early escape of the distraction device. The mean (SD) area of the regenerated bone was 57.1% (26.3) in the experimental site and 41.8% (21.3) in the control site, which was not a statistically significant difference (P > 0.05). The mean (SD) hardness was 0.50 (0.17) MPa in the experiment site and 0.55 (0.29) MPa in the normal calvarial bone; the difference was not statistically significant (P > 0.05). On histologic examination, membranous ossification was found in the regenerated bone in the experimental site. CONCLUSIONS: Transport disc distraction osteogenesis can induce new bone formation with hardness comparable to that of a normal bone. However, the amount of regenerated bone is not sufficient to allow TDDO to be substituted for conventional autogenous bone grafts.

Original languageEnglish
Pages (from-to)790-796
Number of pages7
JournalJournal of Craniofacial Surgery
Volume20
Issue number3
DOIs
Publication statusPublished - 2009 May 1

Fingerprint

Distraction Osteogenesis
Bone and Bones
Hardness
Osteogenesis
Parietal Bone
Equipment and Supplies
Skull

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

Hong, Jong Won ; Song, Seung Yong ; Woo, Dae Gon ; Kim, Han Sung ; Hong, Hyun Joon ; Choi, Joong Ho ; Park, Beyoung Yun ; Kim, Yong Oock. / Transport disc distraction osteogenesis for the reconstruction of a calvarial defect. In: Journal of Craniofacial Surgery. 2009 ; Vol. 20, No. 3. pp. 790-796.
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abstract = "PURPOSE: Reconstruction of bone defects is possible through distraction osteogenesis using small bone transport discs. The aim of this study was to evaluate the usability of transport disc distraction osteogenesis (TDDO) in the reconstruction of skull defects in an animal experiment. METHODS: Eleven mongrel female dogs were used. Craniectomy (33 × 15 mm) was performed on both sides of the parietal bone symmetrically. On the experimental site, the 7 × 15-mm transport bone disc was used for TDDO. The control site was left in the defect state. An external distraction device was used. The latency period was 5 days, the rate of distraction was 1 mm/d, and distraction was done for 26 days. After a 6-month consolidation period, a computed tomographic scan was performed. The area of regenerated bone was measured from the computed tomographic scan. The hardness was checked on the regenerated bone and the normal bone. A histologic examination of the regenerated bone was done. RESULT: Eight cases were included in the evaluation, and 3 cases were excluded because they showed early escape of the distraction device. The mean (SD) area of the regenerated bone was 57.1{\%} (26.3) in the experimental site and 41.8{\%} (21.3) in the control site, which was not a statistically significant difference (P > 0.05). The mean (SD) hardness was 0.50 (0.17) MPa in the experiment site and 0.55 (0.29) MPa in the normal calvarial bone; the difference was not statistically significant (P > 0.05). On histologic examination, membranous ossification was found in the regenerated bone in the experimental site. CONCLUSIONS: Transport disc distraction osteogenesis can induce new bone formation with hardness comparable to that of a normal bone. However, the amount of regenerated bone is not sufficient to allow TDDO to be substituted for conventional autogenous bone grafts.",
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Transport disc distraction osteogenesis for the reconstruction of a calvarial defect. / Hong, Jong Won; Song, Seung Yong; Woo, Dae Gon; Kim, Han Sung; Hong, Hyun Joon; Choi, Joong Ho; Park, Beyoung Yun; Kim, Yong Oock.

In: Journal of Craniofacial Surgery, Vol. 20, No. 3, 01.05.2009, p. 790-796.

Research output: Contribution to journalArticle

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T1 - Transport disc distraction osteogenesis for the reconstruction of a calvarial defect

AU - Hong, Jong Won

AU - Song, Seung Yong

AU - Woo, Dae Gon

AU - Kim, Han Sung

AU - Hong, Hyun Joon

AU - Choi, Joong Ho

AU - Park, Beyoung Yun

AU - Kim, Yong Oock

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N2 - PURPOSE: Reconstruction of bone defects is possible through distraction osteogenesis using small bone transport discs. The aim of this study was to evaluate the usability of transport disc distraction osteogenesis (TDDO) in the reconstruction of skull defects in an animal experiment. METHODS: Eleven mongrel female dogs were used. Craniectomy (33 × 15 mm) was performed on both sides of the parietal bone symmetrically. On the experimental site, the 7 × 15-mm transport bone disc was used for TDDO. The control site was left in the defect state. An external distraction device was used. The latency period was 5 days, the rate of distraction was 1 mm/d, and distraction was done for 26 days. After a 6-month consolidation period, a computed tomographic scan was performed. The area of regenerated bone was measured from the computed tomographic scan. The hardness was checked on the regenerated bone and the normal bone. A histologic examination of the regenerated bone was done. RESULT: Eight cases were included in the evaluation, and 3 cases were excluded because they showed early escape of the distraction device. The mean (SD) area of the regenerated bone was 57.1% (26.3) in the experimental site and 41.8% (21.3) in the control site, which was not a statistically significant difference (P > 0.05). The mean (SD) hardness was 0.50 (0.17) MPa in the experiment site and 0.55 (0.29) MPa in the normal calvarial bone; the difference was not statistically significant (P > 0.05). On histologic examination, membranous ossification was found in the regenerated bone in the experimental site. CONCLUSIONS: Transport disc distraction osteogenesis can induce new bone formation with hardness comparable to that of a normal bone. However, the amount of regenerated bone is not sufficient to allow TDDO to be substituted for conventional autogenous bone grafts.

AB - PURPOSE: Reconstruction of bone defects is possible through distraction osteogenesis using small bone transport discs. The aim of this study was to evaluate the usability of transport disc distraction osteogenesis (TDDO) in the reconstruction of skull defects in an animal experiment. METHODS: Eleven mongrel female dogs were used. Craniectomy (33 × 15 mm) was performed on both sides of the parietal bone symmetrically. On the experimental site, the 7 × 15-mm transport bone disc was used for TDDO. The control site was left in the defect state. An external distraction device was used. The latency period was 5 days, the rate of distraction was 1 mm/d, and distraction was done for 26 days. After a 6-month consolidation period, a computed tomographic scan was performed. The area of regenerated bone was measured from the computed tomographic scan. The hardness was checked on the regenerated bone and the normal bone. A histologic examination of the regenerated bone was done. RESULT: Eight cases were included in the evaluation, and 3 cases were excluded because they showed early escape of the distraction device. The mean (SD) area of the regenerated bone was 57.1% (26.3) in the experimental site and 41.8% (21.3) in the control site, which was not a statistically significant difference (P > 0.05). The mean (SD) hardness was 0.50 (0.17) MPa in the experiment site and 0.55 (0.29) MPa in the normal calvarial bone; the difference was not statistically significant (P > 0.05). On histologic examination, membranous ossification was found in the regenerated bone in the experimental site. CONCLUSIONS: Transport disc distraction osteogenesis can induce new bone formation with hardness comparable to that of a normal bone. However, the amount of regenerated bone is not sufficient to allow TDDO to be substituted for conventional autogenous bone grafts.

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