Objective: The purpose of this study was to evaluate the effects of autogenous bone grafts and platelet-enriched fibrin glue in the treatment of peri-implantitis. Study design: Thirty-six screw-type commercially pure titanium implants with rough acid-etched surfaces were inserted into 6 mongrel dogs 3 months after extraction of mandibular premolars. After 3 months of healing, peri-implantitis was induced by placing gauze and wire around the implants. Once peri-implantitis was created, surgical treatments involving a combination of autogenous bone grafts and platelet-enriched fibrin glue, autogenous bone grafts alone, or a conventional flap procedure only (control) were carried out. Six months later, biopsies of the implant sites were taken and prepared for ground sectioning and analysis. Results: The amount of reosseointegration was significantly higher in peri-implantitis defects treated with combined autogenous bone grafts and platelet-enriched fibrin glue as compared with the other 2 treatment procedures. A mean bone-to-implant contact of 50.1% was obtained in the peri-implantitis lesions treated with combined autogenous bone grafts and platelet-enriched fibrin glue. The corresponding values for the autogenous bone grafts and control groups were 19.3% and 6.5%, respectively. Conclusion: The present study demonstrates that surgical treatment involving the combined use of autogenous bone grafts and platelet-enriched fibrin glue might effectively promote reosseointegration in lesions resulting from peri-implantitis.
|Number of pages||4|
|Journal||Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics|
|Publication status||Published - 2007 Jan|
Bibliographical noteFunding Information:
Supported by grant no. R13-2003-13 from the Medical Science and Engineering Research Program of the Korea Science & Engineering Foundation.
All Science Journal Classification (ASJC) codes
- Oral Surgery