Abstract
Early esophageal cancer (EEC) has an excellent prognosis compared to advanced esophageal cancer. Nowadays, endoscopic mucosal resection (EMR) may offer another alternative to cure early cancers of the gastrointestinal tract. We aimed to evaluate the clinical outcomes of EEC in Korea after curative treatments; EMR or surgery. We retrospectively reviewed the medical records of patients diagnosed as EEC from January 1994 to August 2005 at Yonsei University Medical Center, Seoul, Korea. Among 888 patients diagnosed with esophageal cancer, 70 (7.9%) were included as EEC. Among them, 10 patients (14.3%) were treated by EMR, and 50 (71.4%) by operation. The treatment outcomes of EEC in relation to various clinicopathologic factors along with survival rates were analyzed. There were 18 cases (30%) of mucosal lesions and 42 cases (70%) of submucosal lesions. Overall 5-year survival rate was 84.3%. When comparing treatment outcomes between EMR-treated and operated groups, there were no significant differences in complete remission (80% vs. 84%), recurrence (20% vs. 16%) and 5-year survival rate (100% vs. 78.3%). EEC is a potentially curable entity with a good clinical prognosis. EMR can be considered as another treatment arm for EEC, along with surgical resection.
| Original language | English |
|---|---|
| Pages (from-to) | 297-300 |
| Number of pages | 4 |
| Journal | Diseases of the Esophagus |
| Volume | 20 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2007 Aug 1 |
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All Science Journal Classification (ASJC) codes
- Gastroenterology
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Treatment outcomes of 70 cases of early esophageal carcinoma : 12 years of experience. / Kim, J. H.; Chung, H. S.; Youn, Y. H.; Park, S. W.; Song, S. Y.; Chung, J. B.; Kim, C. B.; Lee, Yong Chan.
In: Diseases of the Esophagus, Vol. 20, No. 4, 01.08.2007, p. 297-300.Research output: Contribution to journal › Article
TY - JOUR
T1 - Treatment outcomes of 70 cases of early esophageal carcinoma
T2 - 12 years of experience
AU - Kim, J. H.
AU - Chung, H. S.
AU - Youn, Y. H.
AU - Park, S. W.
AU - Song, S. Y.
AU - Chung, J. B.
AU - Kim, C. B.
AU - Lee, Yong Chan
PY - 2007/8/1
Y1 - 2007/8/1
N2 - Early esophageal cancer (EEC) has an excellent prognosis compared to advanced esophageal cancer. Nowadays, endoscopic mucosal resection (EMR) may offer another alternative to cure early cancers of the gastrointestinal tract. We aimed to evaluate the clinical outcomes of EEC in Korea after curative treatments; EMR or surgery. We retrospectively reviewed the medical records of patients diagnosed as EEC from January 1994 to August 2005 at Yonsei University Medical Center, Seoul, Korea. Among 888 patients diagnosed with esophageal cancer, 70 (7.9%) were included as EEC. Among them, 10 patients (14.3%) were treated by EMR, and 50 (71.4%) by operation. The treatment outcomes of EEC in relation to various clinicopathologic factors along with survival rates were analyzed. There were 18 cases (30%) of mucosal lesions and 42 cases (70%) of submucosal lesions. Overall 5-year survival rate was 84.3%. When comparing treatment outcomes between EMR-treated and operated groups, there were no significant differences in complete remission (80% vs. 84%), recurrence (20% vs. 16%) and 5-year survival rate (100% vs. 78.3%). EEC is a potentially curable entity with a good clinical prognosis. EMR can be considered as another treatment arm for EEC, along with surgical resection.
AB - Early esophageal cancer (EEC) has an excellent prognosis compared to advanced esophageal cancer. Nowadays, endoscopic mucosal resection (EMR) may offer another alternative to cure early cancers of the gastrointestinal tract. We aimed to evaluate the clinical outcomes of EEC in Korea after curative treatments; EMR or surgery. We retrospectively reviewed the medical records of patients diagnosed as EEC from January 1994 to August 2005 at Yonsei University Medical Center, Seoul, Korea. Among 888 patients diagnosed with esophageal cancer, 70 (7.9%) were included as EEC. Among them, 10 patients (14.3%) were treated by EMR, and 50 (71.4%) by operation. The treatment outcomes of EEC in relation to various clinicopathologic factors along with survival rates were analyzed. There were 18 cases (30%) of mucosal lesions and 42 cases (70%) of submucosal lesions. Overall 5-year survival rate was 84.3%. When comparing treatment outcomes between EMR-treated and operated groups, there were no significant differences in complete remission (80% vs. 84%), recurrence (20% vs. 16%) and 5-year survival rate (100% vs. 78.3%). EEC is a potentially curable entity with a good clinical prognosis. EMR can be considered as another treatment arm for EEC, along with surgical resection.
UR - http://www.scopus.com/inward/record.url?scp=34447305448&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34447305448&partnerID=8YFLogxK
U2 - 10.1111/j.1442-2050.2007.00674.x
DO - 10.1111/j.1442-2050.2007.00674.x
M3 - Article
C2 - 17617877
AN - SCOPUS:34447305448
VL - 20
SP - 297
EP - 300
JO - Diseases of the Esophagus
JF - Diseases of the Esophagus
SN - 1120-8694
IS - 4
ER -