Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma

Ki Hyun Park, Jeong Yeon Kim, Jong Seung Shin, Ja Young Kwon, Ja Seong Koo, Kyung Ah Jeong, Namhoon Cho, Sang Wook Bai, Byung Seok Lee

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

In treating women with leiomyoma and who wish to preserve their uterus, laparoscopic uterine artery ligation or uterine artery embolization should be considered as possible options. This study was performed to evaluate the efficacy of laparoscopic uterine artery ligation and uterine artery embolization in treating uterine myoma. The treatment outcomes of 23 patients who underwent uterine artery embolization and 17 laparoscopic uterine artery ligation were evaluated. The uterine volume reduced 3 months after uterine artery embolization, but thereafter no significant changes were observed. On the other hand, the uterine volumes were only slightly reduced 3 months after laparoscopic uterine artery ligation, and slightly more reduced 6 months later. The average reduction in the case of laparoscopic uterine artery ligation was about 58.5%. After laparoscopic uterine artery ligation, 20% of the patients complained of vaginal spotting. Furthermore, the mechanism of volume reduction was evaluated using specimens obtained from a biopsy taken after each procedure. The results suggested that laparoscopic uterine artery ligation results mainly in physiologic cell death, that is apoptosis, whereas, the corresponding result is cell necrosis for uterine artery embolization. Uterine artery embolization and laparoscopic uterine artery ligation are both effective in relieving the symptoms caused by uterine myoma, and therefore both procedures can be used in place of hysterectomy or myomectomy.

Original languageEnglish
Pages (from-to)694-702
Number of pages9
JournalYonsei medical journal
Volume44
Issue number4
DOIs
Publication statusPublished - 2003 Aug 30

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Uterine Artery Embolization
Uterine Artery
Myoma
Ligation
Uterine Myomectomy
Metrorrhagia
Leiomyoma
Hysterectomy
Uterus
Cell Death
Necrosis
Apoptosis
Biopsy

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Park, K. H., Kim, J. Y., Shin, J. S., Kwon, J. Y., Koo, J. S., Jeong, K. A., ... Lee, B. S. (2003). Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma. Yonsei medical journal, 44(4), 694-702. https://doi.org/10.3349/ymj.2003.44.4.694
Park, Ki Hyun ; Kim, Jeong Yeon ; Shin, Jong Seung ; Kwon, Ja Young ; Koo, Ja Seong ; Jeong, Kyung Ah ; Cho, Namhoon ; Bai, Sang Wook ; Lee, Byung Seok. / Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma. In: Yonsei medical journal. 2003 ; Vol. 44, No. 4. pp. 694-702.
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Treatment outcomes of uterine artery embolization and laparoscopic uterine artery ligation for uterine myoma. / Park, Ki Hyun; Kim, Jeong Yeon; Shin, Jong Seung; Kwon, Ja Young; Koo, Ja Seong; Jeong, Kyung Ah; Cho, Namhoon; Bai, Sang Wook; Lee, Byung Seok.

In: Yonsei medical journal, Vol. 44, No. 4, 30.08.2003, p. 694-702.

Research output: Contribution to journalArticle

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