Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene

Yong Chan Kim, Min Hyung Kim, Je Eun Song, Jin Young Ahn, Dong Hyun Oh, Oh Mee Kweon, Dongsuk Lee, Sun Bean Kim, Hye Won Kim, Su Jin Jeong, Nam Su Ku, Sang Hoon Han, Eun Suk Park, Dongeun Yong, Young Goo Song, Kyungwon Lee, June Myung Kim, Jun Yong Choi

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. Methods: Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65%. The computerized prescription restriction was implemented in August 2008. "Hand hygiene program," consistent with World Health Organization guideline, was reinforced in December 2008. We assessed the effect of the infection control programs on the incidence of MRSA bloodstream infection (BSI) from January 2006 through November 2011. Results: Incidence of MRSA BSI was reduced from 0.171 per 1,000 patient-days in 2009 to 0.116 per 1,000 patient-days in 2011 (P =.009). Monthly mean antibiotic consumption decreased from 690.54 ± 28.33 defined daily dose per 1,000 patients-days in 2008 to 652.47 ± 20.77 (P =.015) in 2011. The rates of performance in hand hygiene increased from 43% in 2008 to 83% in 2011 (P =.043). Conclusion: Although we did not implement all components of "MRSA bundle," efforts to reinforce antibiotic stewardship and hand hygiene program for 3 years had beneficial effects on the decrease in MRSA BSI in this institute with high rate of MRSA.

Original languageEnglish
Pages (from-to)e39-e43
JournalAmerican Journal of Infection Control
Volume41
Issue number5
DOIs
Publication statusPublished - 2013 May 1

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Hand Hygiene
Methicillin-Resistant Staphylococcus aureus
Bacteremia
Anti-Bacterial Agents
Infection
Republic of Korea
Methicillin Resistance
Incidence
Infection Control
Tertiary Care Centers
Prescriptions
Staphylococcus aureus
Guidelines

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Kim, Yong Chan ; Kim, Min Hyung ; Song, Je Eun ; Ahn, Jin Young ; Oh, Dong Hyun ; Kweon, Oh Mee ; Lee, Dongsuk ; Kim, Sun Bean ; Kim, Hye Won ; Jeong, Su Jin ; Ku, Nam Su ; Han, Sang Hoon ; Park, Eun Suk ; Yong, Dongeun ; Song, Young Goo ; Lee, Kyungwon ; Kim, June Myung ; Choi, Jun Yong. / Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene. In: American Journal of Infection Control. 2013 ; Vol. 41, No. 5. pp. e39-e43.
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title = "Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene",
abstract = "Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. Methods: Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65{\%}. The computerized prescription restriction was implemented in August 2008. {"}Hand hygiene program,{"} consistent with World Health Organization guideline, was reinforced in December 2008. We assessed the effect of the infection control programs on the incidence of MRSA bloodstream infection (BSI) from January 2006 through November 2011. Results: Incidence of MRSA BSI was reduced from 0.171 per 1,000 patient-days in 2009 to 0.116 per 1,000 patient-days in 2011 (P =.009). Monthly mean antibiotic consumption decreased from 690.54 ± 28.33 defined daily dose per 1,000 patients-days in 2008 to 652.47 ± 20.77 (P =.015) in 2011. The rates of performance in hand hygiene increased from 43{\%} in 2008 to 83{\%} in 2011 (P =.043). Conclusion: Although we did not implement all components of {"}MRSA bundle,{"} efforts to reinforce antibiotic stewardship and hand hygiene program for 3 years had beneficial effects on the decrease in MRSA BSI in this institute with high rate of MRSA.",
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Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene. / Kim, Yong Chan; Kim, Min Hyung; Song, Je Eun; Ahn, Jin Young; Oh, Dong Hyun; Kweon, Oh Mee; Lee, Dongsuk; Kim, Sun Bean; Kim, Hye Won; Jeong, Su Jin; Ku, Nam Su; Han, Sang Hoon; Park, Eun Suk; Yong, Dongeun; Song, Young Goo; Lee, Kyungwon; Kim, June Myung; Choi, Jun Yong.

In: American Journal of Infection Control, Vol. 41, No. 5, 01.05.2013, p. e39-e43.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene

AU - Kim, Yong Chan

AU - Kim, Min Hyung

AU - Song, Je Eun

AU - Ahn, Jin Young

AU - Oh, Dong Hyun

AU - Kweon, Oh Mee

AU - Lee, Dongsuk

AU - Kim, Sun Bean

AU - Kim, Hye Won

AU - Jeong, Su Jin

AU - Ku, Nam Su

AU - Han, Sang Hoon

AU - Park, Eun Suk

AU - Yong, Dongeun

AU - Song, Young Goo

AU - Lee, Kyungwon

AU - Kim, June Myung

AU - Choi, Jun Yong

PY - 2013/5/1

Y1 - 2013/5/1

N2 - Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. Methods: Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65%. The computerized prescription restriction was implemented in August 2008. "Hand hygiene program," consistent with World Health Organization guideline, was reinforced in December 2008. We assessed the effect of the infection control programs on the incidence of MRSA bloodstream infection (BSI) from January 2006 through November 2011. Results: Incidence of MRSA BSI was reduced from 0.171 per 1,000 patient-days in 2009 to 0.116 per 1,000 patient-days in 2011 (P =.009). Monthly mean antibiotic consumption decreased from 690.54 ± 28.33 defined daily dose per 1,000 patients-days in 2008 to 652.47 ± 20.77 (P =.015) in 2011. The rates of performance in hand hygiene increased from 43% in 2008 to 83% in 2011 (P =.043). Conclusion: Although we did not implement all components of "MRSA bundle," efforts to reinforce antibiotic stewardship and hand hygiene program for 3 years had beneficial effects on the decrease in MRSA BSI in this institute with high rate of MRSA.

AB - Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. Methods: Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65%. The computerized prescription restriction was implemented in August 2008. "Hand hygiene program," consistent with World Health Organization guideline, was reinforced in December 2008. We assessed the effect of the infection control programs on the incidence of MRSA bloodstream infection (BSI) from January 2006 through November 2011. Results: Incidence of MRSA BSI was reduced from 0.171 per 1,000 patient-days in 2009 to 0.116 per 1,000 patient-days in 2011 (P =.009). Monthly mean antibiotic consumption decreased from 690.54 ± 28.33 defined daily dose per 1,000 patients-days in 2008 to 652.47 ± 20.77 (P =.015) in 2011. The rates of performance in hand hygiene increased from 43% in 2008 to 83% in 2011 (P =.043). Conclusion: Although we did not implement all components of "MRSA bundle," efforts to reinforce antibiotic stewardship and hand hygiene program for 3 years had beneficial effects on the decrease in MRSA BSI in this institute with high rate of MRSA.

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