A mild, convenient, and efficient one-pot synthesis of mercapto-1,2,4- triazoles is described. Various hydrazides efficiently reacted with trimethylsilyl isothiocyanate (TMSNCS) under basic condition to give mercapto-1,2,4-triazoles in high yields.
|Number of pages||5|
|Publication status||Published - 2012 Sept 26|
Bibliographical noteFunding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2010-0024877). We thank Professor Robert West, distinguished Professor in the WCU program for his valuable discussion. D.R. Guda also thanks BK-21 funds for the financial support of his post-doc position.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry