Tumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function

Medicine and Dentistry

• Cells 93%
• Neoplasm 46%
• Death 40%
• T Cell 33%
• Tumor Microenvironment 26%
• Immunosuppressive Drug 20%
• Lung Cancer 20%
• Patient 20%
• Blood 20%
• Phenotype 13%
• Malignant Neoplasm 13%
• Immunoglobulin 13%
• Effusion 6%
• Cell Type 6%
• Upregulation 6%
• Antibody 6%
• Cancer Model 6%
• Lymphocyte 6%
• Mucin 6%
• CTLA-4 6%
• Immunosuppressive Treatment 6%
• Cancer Therapy 6%
• Tissues 6%
• Assay 6%
• Regulatory T Cell 6%

Immunology and Microbiology

• Cells 100%
• Regulatory T Cell 93%
• Immunity 46%
• Molecule 40%
• Immunosuppressive Drug 20%
• Lung 20%
• Phenotype 13%
• Intravenous Immunoglobulin 13%
• T Cell Subset 13%
• T-Helper Cell 13%
• Mouse Model 6%
• Upregulation 6%
• Monospecific Antibody 6%
• CD8 6%
• CTLA-4 6%
• Tissues 6%
• Time 6%
• Mouse 6%
• Immunosuppression 6%

Biochemistry, Genetics and Molecular Biology

• T Cell 66%
• Molecule 40%
• Phenotype 13%
• Regulatory T Cell 6%
• Upregulation 6%
• CD8 6%
• Mouse 6%
• Time 6%