Tumor-targeting gold particles for dual computed tomography/optical cancer imaging

In Cheol Sun, Dae Kyung Eun, Heebeom Koo, Chang Yong Ko, Han Sung Kim, Dong Kee Yi, Kuiwon Choi, Ick Chan Kwon, Kwangmeyung Kim, Cheol Hee Ahn

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92 Citations (Scopus)

Abstract

Double spotlight: A dual imaging probe with gold nanoparticles (AuNPs) for computed tomography (CT) and optical imaging exhibits have been developed (see picture). The excellent stability, tumor targeting ability, enhanced X-ray absorption, and matrix metalloproteinase (MMP) activatable fluorescence recovery was achieved by surface modification of AuNPs with glycol chitosan and fluorescent MMP peptide probes.

Original languageEnglish
Pages (from-to)9348-9351
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number40
DOIs
Publication statusPublished - 2011 Sep 26

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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    Sun, I. C., Eun, D. K., Koo, H., Ko, C. Y., Kim, H. S., Yi, D. K., Choi, K., Kwon, I. C., Kim, K., & Ahn, C. H. (2011). Tumor-targeting gold particles for dual computed tomography/optical cancer imaging. Angewandte Chemie - International Edition, 50(40), 9348-9351. https://doi.org/10.1002/anie.201102892