Two cases of anti-p200 pemphigoid

Mi Ri Kim, Jae Yong Chang, Soo Chan Kim

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Abstract

Anti-p200 pemphigoid is a recently defined subepidermal immunobullous disease. Most anti-p200 pemphigoid patients show the clinical features of bullous pemphigoid, dermatitis herpetiformis and linear IgA disease. It is characterized by the binding of circulating IgG autoantibodies to the dermal side of 1 M NaCl split skin, and by reactivity of these autoantibodies to a unique 200-kD antigen on immunoblot of dermal extract. On immunoelectron microscopic examination, these autoantibodies deposit at the lamina lucida-lamina densa interface. Herein, we report two cases of anti-p200 pemphigoid, as well as their favorable response to treatment with systemic corticosteroid, colchicine and dapsone.

Original languageEnglish
Pages (from-to)821-825
Number of pages5
JournalKorean Journal of Dermatology
Volume46
Issue number6
Publication statusPublished - 2008 Jun 1

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All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Kim, M. R., Chang, J. Y., & Kim, S. C. (2008). Two cases of anti-p200 pemphigoid. Korean Journal of Dermatology, 46(6), 821-825.