Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions

Myeongki Hong, Cheol Whan Lee, Young Hak Kim, Bong Ki Lee, Min Kyu Kim, Tae Hyun Yang, Jong Min Song, Ki Hoon Han, Duk Hyun Kang, Jae Kwan Song, Jae Joong Kim, Seong Wook Park, Seung Jung Park

Research output: Contribution to journalArticle

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Abstract

The objective of this study was to examine long-term changes after bare metal stent implantation in a relatively large number of patients. There are few reports of intravascular ultrasound (IVUS) studies performed on stented and nonstented (reference) segments beyond 6 months after bare metal stenting. Using IVUS, we evaluated serial changes in stented and reference segments between 6 and 24 months after stent implantation in 110 patients with 120 lesions. Serial IVUS images were acquired at five equidistant intrastent sites and at two different reference segment sites. Measurements were made of the external elastic membrane (EEM), stent, lumen, and intimal hyperplasia (IH = stent - lumen) area. For the whole patient group, between 6 and 24 months, the mean IH area in stented segments decreased from 2.6 ± 1.0 to 2.3 ± 0.9 mm 2 (P < 0.001), and the mean lumen area increased from 6.2 ± 2.0 to 6.5 ± 1.9 mm 2 (P < 0.001). The mean IH area decreased in 91 lesions (76%) and increased in 29 lesions (24%) between 6 and 24 months. There were no significant changes in EEM or lumen area in the reference segments. Late angiographic restenosis (diameter stenosis ≥ 50%) occurred in three lesions between 6 and 24 months. A late target lesion revascularization was performed for one lesion. In the period of time between 6 and 24 months after stenting, IH regression occurred in most (76%) stent lesions, resulting in late lumen increase. However, IH progression was observed in 24% of instent lesions. No significant changes of EEM or lumen area occurred in the reference segments.

Original languageEnglish
Pages (from-to)247-253
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Volume65
Issue number2
DOIs
Publication statusPublished - 2005 Jun 1

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Stents
Metals
Membranes
Tunica Intima
Hyperplasia
Pathologic Constriction

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Hong, Myeongki ; Lee, Cheol Whan ; Kim, Young Hak ; Lee, Bong Ki ; Kim, Min Kyu ; Yang, Tae Hyun ; Song, Jong Min ; Han, Ki Hoon ; Kang, Duk Hyun ; Song, Jae Kwan ; Kim, Jae Joong ; Park, Seong Wook ; Park, Seung Jung. / Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions. In: Catheterization and Cardiovascular Interventions. 2005 ; Vol. 65, No. 2. pp. 247-253.
@article{a70e5d09f674433fbf28000d8cbc0601,
title = "Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions",
abstract = "The objective of this study was to examine long-term changes after bare metal stent implantation in a relatively large number of patients. There are few reports of intravascular ultrasound (IVUS) studies performed on stented and nonstented (reference) segments beyond 6 months after bare metal stenting. Using IVUS, we evaluated serial changes in stented and reference segments between 6 and 24 months after stent implantation in 110 patients with 120 lesions. Serial IVUS images were acquired at five equidistant intrastent sites and at two different reference segment sites. Measurements were made of the external elastic membrane (EEM), stent, lumen, and intimal hyperplasia (IH = stent - lumen) area. For the whole patient group, between 6 and 24 months, the mean IH area in stented segments decreased from 2.6 ± 1.0 to 2.3 ± 0.9 mm 2 (P < 0.001), and the mean lumen area increased from 6.2 ± 2.0 to 6.5 ± 1.9 mm 2 (P < 0.001). The mean IH area decreased in 91 lesions (76{\%}) and increased in 29 lesions (24{\%}) between 6 and 24 months. There were no significant changes in EEM or lumen area in the reference segments. Late angiographic restenosis (diameter stenosis ≥ 50{\%}) occurred in three lesions between 6 and 24 months. A late target lesion revascularization was performed for one lesion. In the period of time between 6 and 24 months after stenting, IH regression occurred in most (76{\%}) stent lesions, resulting in late lumen increase. However, IH progression was observed in 24{\%} of instent lesions. No significant changes of EEM or lumen area occurred in the reference segments.",
author = "Myeongki Hong and Lee, {Cheol Whan} and Kim, {Young Hak} and Lee, {Bong Ki} and Kim, {Min Kyu} and Yang, {Tae Hyun} and Song, {Jong Min} and Han, {Ki Hoon} and Kang, {Duk Hyun} and Song, {Jae Kwan} and Kim, {Jae Joong} and Park, {Seong Wook} and Park, {Seung Jung}",
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Hong, M, Lee, CW, Kim, YH, Lee, BK, Kim, MK, Yang, TH, Song, JM, Han, KH, Kang, DH, Song, JK, Kim, JJ, Park, SW & Park, SJ 2005, 'Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions', Catheterization and Cardiovascular Interventions, vol. 65, no. 2, pp. 247-253. https://doi.org/10.1002/ccd.20358

Two-year follow-up intravascular ultrasound analysis after bare metal stent implantation in 120 lesions. / Hong, Myeongki; Lee, Cheol Whan; Kim, Young Hak; Lee, Bong Ki; Kim, Min Kyu; Yang, Tae Hyun; Song, Jong Min; Han, Ki Hoon; Kang, Duk Hyun; Song, Jae Kwan; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.

In: Catheterization and Cardiovascular Interventions, Vol. 65, No. 2, 01.06.2005, p. 247-253.

Research output: Contribution to journalArticle

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AU - Hong, Myeongki

AU - Lee, Cheol Whan

AU - Kim, Young Hak

AU - Lee, Bong Ki

AU - Kim, Min Kyu

AU - Yang, Tae Hyun

AU - Song, Jong Min

AU - Han, Ki Hoon

AU - Kang, Duk Hyun

AU - Song, Jae Kwan

AU - Kim, Jae Joong

AU - Park, Seong Wook

AU - Park, Seung Jung

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N2 - The objective of this study was to examine long-term changes after bare metal stent implantation in a relatively large number of patients. There are few reports of intravascular ultrasound (IVUS) studies performed on stented and nonstented (reference) segments beyond 6 months after bare metal stenting. Using IVUS, we evaluated serial changes in stented and reference segments between 6 and 24 months after stent implantation in 110 patients with 120 lesions. Serial IVUS images were acquired at five equidistant intrastent sites and at two different reference segment sites. Measurements were made of the external elastic membrane (EEM), stent, lumen, and intimal hyperplasia (IH = stent - lumen) area. For the whole patient group, between 6 and 24 months, the mean IH area in stented segments decreased from 2.6 ± 1.0 to 2.3 ± 0.9 mm 2 (P < 0.001), and the mean lumen area increased from 6.2 ± 2.0 to 6.5 ± 1.9 mm 2 (P < 0.001). The mean IH area decreased in 91 lesions (76%) and increased in 29 lesions (24%) between 6 and 24 months. There were no significant changes in EEM or lumen area in the reference segments. Late angiographic restenosis (diameter stenosis ≥ 50%) occurred in three lesions between 6 and 24 months. A late target lesion revascularization was performed for one lesion. In the period of time between 6 and 24 months after stenting, IH regression occurred in most (76%) stent lesions, resulting in late lumen increase. However, IH progression was observed in 24% of instent lesions. No significant changes of EEM or lumen area occurred in the reference segments.

AB - The objective of this study was to examine long-term changes after bare metal stent implantation in a relatively large number of patients. There are few reports of intravascular ultrasound (IVUS) studies performed on stented and nonstented (reference) segments beyond 6 months after bare metal stenting. Using IVUS, we evaluated serial changes in stented and reference segments between 6 and 24 months after stent implantation in 110 patients with 120 lesions. Serial IVUS images were acquired at five equidistant intrastent sites and at two different reference segment sites. Measurements were made of the external elastic membrane (EEM), stent, lumen, and intimal hyperplasia (IH = stent - lumen) area. For the whole patient group, between 6 and 24 months, the mean IH area in stented segments decreased from 2.6 ± 1.0 to 2.3 ± 0.9 mm 2 (P < 0.001), and the mean lumen area increased from 6.2 ± 2.0 to 6.5 ± 1.9 mm 2 (P < 0.001). The mean IH area decreased in 91 lesions (76%) and increased in 29 lesions (24%) between 6 and 24 months. There were no significant changes in EEM or lumen area in the reference segments. Late angiographic restenosis (diameter stenosis ≥ 50%) occurred in three lesions between 6 and 24 months. A late target lesion revascularization was performed for one lesion. In the period of time between 6 and 24 months after stenting, IH regression occurred in most (76%) stent lesions, resulting in late lumen increase. However, IH progression was observed in 24% of instent lesions. No significant changes of EEM or lumen area occurred in the reference segments.

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