Ultrasonographic findings of Kimura’s disease presenting in the upper extremities

Gi Won Shin, Sun Joo Lee, Hye Jung Choo, Young Mi Park, Hae Woong Jeong, Sung Moon Lee, Jin Suck Suh, Soo Jin Jung

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4 Citations (Scopus)


Objective: To describe ultrasound findings of Kimura’s disease arising in the upper extremities.

Materials and methods: Five patients with Kimura’s disease confirmed by surgical resection were retrospectively reviewed by two musculoskeletal radiologists and a pathologist.

Results: All six lesions involved the epitrochlear area and appeared as partially (n = 5) or poorly (n = 1) marginated subcutaneous masses with the presence of curvilinear hyperechoic bands intermingled within the hypoechoic components by US. Moderate (n = 4) to severe (n = 2) vascular signals were observed in some proportion of the hyperechoic bands by color Doppler US. The associated findings were the increased echogenicity of surrounding subcutaneous fat (n = 6) and adjacent lymphadenopathy (n = 4). Microscopic examination showed proliferation of lymphoid follicles with prominent germinal centers and intervening fibrosis.

Conclusions: In this study, Kimura’s disease arising in the upper extremities showed a partially defined hypoechoic subcutaneous mass with internal hyperechoic bands and moderate-to-severe vascularities, increased echogenicity of the surrounding subcutaneous fat and adjacent lymphadenopathy on US. Thus, when these US features are observed in the typical epitrochlear region of an Asian individual, especially if accompanied by peripheral eosinophilia, Kimura’s disease should be considered as a possible diagnosis.

Original languageEnglish
Pages (from-to)692-699
Number of pages8
JournalJapanese Journal of Radiology
Issue number12
Publication statusPublished - 2014 Dec 18

Bibliographical note

Funding Information:
Acknowledgments This work was supported by the 2013 Inje University research grant.

Publisher Copyright:
© 2014, Japan Radiological Society.

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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