Ultrasonographic investigation of cholangiocarcinoma in Lao PDR

Ju Yeong Kim, Tai Soon Yong, Han Jong Rim, Jong Yil Chai, Duk Young Min, Keeseon S. Eom, Woon Mok Sohn, Jae Hoon Lim, Dongil Choi, Sithat Insisiengmay, Bounlay Phommasack, Bounnaloth Insisiengmay

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3 Citations (Scopus)

Abstract

Opisthorchis viverrini is a group 1 carcinogen that causes cholangiocarcinoma (CCA). Although opisthorchiasis is known to be severely endemic to several areas along the Mekong River in Lao PDR, the CCA status of residents of this region is still under investigation. In this study, we analyzed the results of abdominal ultrasonography (US) performed on 6113 residents in 9 provinces (Vientiane Municipality, Savannakhet, Phongsaly, Khammouane, Saravane, Champasak, Vientiane, Xieng Khuouang, and Luang Prabang provinces) of Lao PDR from 2007 to 2011. Overall, 51 cases (0.83%) were detected with suspected CCA. The CCA rates in Vientiane Municipality and in Savannakhet and Khammouane provinces were 1.45%, 1.58%, and 1.09%, respectively. However, in the other 6 provinces, the rate of CCA averaged only 0.26%. In the 3 provinces with higher rates of CCA, bile duct dilatation (grade ≥ 2) was also significantly more prevalent (P < 0.0001). These results are concordant with previous reports showing a higher endemicity of opisthorchiasis in Vientiane Municipality and in Savannakhet and Khammouane provinces.

Original languageEnglish
Pages (from-to)128-134
Number of pages7
JournalActa Tropica
Volume182
DOIs
Publication statusPublished - 2018 Jun

All Science Journal Classification (ASJC) codes

  • Parasitology
  • veterinary (miscalleneous)
  • Insect Science
  • Infectious Diseases

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    Kim, J. Y., Yong, T. S., Rim, H. J., Chai, J. Y., Min, D. Y., Eom, K. S., Sohn, W. M., Lim, J. H., Choi, D., Insisiengmay, S., Phommasack, B., & Insisiengmay, B. (2018). Ultrasonographic investigation of cholangiocarcinoma in Lao PDR. Acta Tropica, 182, 128-134. https://doi.org/10.1016/j.actatropica.2018.02.031