Reciprocal interactions between tumor cells and their microenvironment drive cancer progression and therapy resistance. In this issue, Nabet et al. demonstrate that dynamic feedback between tumor and stroma subverts normal inflammatory responses by triggering the release of exosomes containing unshielded RNAs that activate pattern recognition receptors, thereby promoting tumor growth and metastasis.
|Number of pages||3|
|Publication status||Published - 2017 Jul 13|
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All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)