Abstract
Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions.
| Original language | English |
|---|---|
| Pages (from-to) | 511-515 |
| Number of pages | 5 |
| Journal | Clinical Endoscopy |
| Volume | 48 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2015 Jan 1 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Gastroenterology
- Radiology Nuclear Medicine and imaging
Cite this
}
Usefulness and future prospects of confocal laser endomicroscopy for gastric premalignant and malignant lesions. / Lee, Sang Kil.
In: Clinical Endoscopy, Vol. 48, No. 6, 01.01.2015, p. 511-515.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Usefulness and future prospects of confocal laser endomicroscopy for gastric premalignant and malignant lesions
AU - Lee, Sang Kil
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions.
AB - Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions.
UR - http://www.scopus.com/inward/record.url?scp=84948654025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948654025&partnerID=8YFLogxK
U2 - 10.5946/ce.2015.48.6.511
DO - 10.5946/ce.2015.48.6.511
M3 - Review article
AN - SCOPUS:84948654025
VL - 48
SP - 511
EP - 515
JO - Clinical Endoscopy
JF - Clinical Endoscopy
SN - 2234-2400
IS - 6
ER -