Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis: Findings from the EPI-PSODE study

Yong Beom Choe, Chul Jong Park, Dae Young Yu, Youngdoe Kim, Hyun Jeong Ju, Sang Woong Youn, Joo Heung Lee, Byung Soo Kim, Seong Jun Seo, Seok Kweon Yun, Joonsoo Park, Nack In Kim, Jai Il Youn, Seok Jong Lee, Mingeol Lee, Kwang Joong Kim, Young Suck Ro, Hae Jun Song, Bong Seok Shin, Sung Ku AhnJi Yeoun Lee, Young Ho Won, Min Soo Jang, Ki Ho Kim, Myung Hwa Kim, Tae Yoon Kim, Jee Ho Choi

Research output: Contribution to journalArticle

Abstract

Background: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited. Objective: To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis. Methods: This was a multicenter, non-interventional, cross-sectional study. Demographic factors and PASI and PASE scores were collected to investigate associations between each. Results: PASE data were available for 1,255 patients, of whom 498 (39.7%) had a score of ≥37. Compared with the group with PASE score <37, the group with score ≥37 had a higher proportion of women (34.9% vs. 48.8%, p<0.0001), older mean age at diagnosis (36.4 vs. 41.7 years, p<0.0001), more severe disease activity using PASI and body surface area measures (p=0.0021 and p=0.0008, respectively), and higher mean body mass index (23.7 vs. 24.1, p=0.0411). In a multiple linear regression model, PASE score was positively associated with cutaneous disease activity (p<0.0001). Conclusion: After risk-adjustment, PASE was positively associated with PASI, which suggests that PASE can be sensitive to disease activity. Since psoriasis is regarded as one of the IMIDs, PASE may be utilized as a tool not only to screen PsA but also to monitor disease activity.

Original languageEnglish
Pages (from-to)29-36
Number of pages8
JournalAnnals of Dermatology
Volume31
Issue number1
DOIs
Publication statusPublished - 2019 Feb 1

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Psoriatic Arthritis
Psoriasis
Linear Models
Surveys and Questionnaires
Risk Adjustment
Body Surface Area
Skin Diseases
Body Mass Index
Cross-Sectional Studies
Demography
Inflammation

All Science Journal Classification (ASJC) codes

  • Dermatology

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Choe, Yong Beom ; Park, Chul Jong ; Yu, Dae Young ; Kim, Youngdoe ; Ju, Hyun Jeong ; Youn, Sang Woong ; Lee, Joo Heung ; Kim, Byung Soo ; Seo, Seong Jun ; Yun, Seok Kweon ; Park, Joonsoo ; Kim, Nack In ; Youn, Jai Il ; Lee, Seok Jong ; Lee, Mingeol ; Kim, Kwang Joong ; Ro, Young Suck ; Song, Hae Jun ; Shin, Bong Seok ; Ahn, Sung Ku ; Lee, Ji Yeoun ; Won, Young Ho ; Jang, Min Soo ; Kim, Ki Ho ; Kim, Myung Hwa ; Kim, Tae Yoon ; Choi, Jee Ho. / Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis : Findings from the EPI-PSODE study. In: Annals of Dermatology. 2019 ; Vol. 31, No. 1. pp. 29-36.
@article{1200903a956b4b6d8fe8ff59685ad564,
title = "Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis: Findings from the EPI-PSODE study",
abstract = "Background: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited. Objective: To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis. Methods: This was a multicenter, non-interventional, cross-sectional study. Demographic factors and PASI and PASE scores were collected to investigate associations between each. Results: PASE data were available for 1,255 patients, of whom 498 (39.7{\%}) had a score of ≥37. Compared with the group with PASE score <37, the group with score ≥37 had a higher proportion of women (34.9{\%} vs. 48.8{\%}, p<0.0001), older mean age at diagnosis (36.4 vs. 41.7 years, p<0.0001), more severe disease activity using PASI and body surface area measures (p=0.0021 and p=0.0008, respectively), and higher mean body mass index (23.7 vs. 24.1, p=0.0411). In a multiple linear regression model, PASE score was positively associated with cutaneous disease activity (p<0.0001). Conclusion: After risk-adjustment, PASE was positively associated with PASI, which suggests that PASE can be sensitive to disease activity. Since psoriasis is regarded as one of the IMIDs, PASE may be utilized as a tool not only to screen PsA but also to monitor disease activity.",
author = "Choe, {Yong Beom} and Park, {Chul Jong} and Yu, {Dae Young} and Youngdoe Kim and Ju, {Hyun Jeong} and Youn, {Sang Woong} and Lee, {Joo Heung} and Kim, {Byung Soo} and Seo, {Seong Jun} and Yun, {Seok Kweon} and Joonsoo Park and Kim, {Nack In} and Youn, {Jai Il} and Lee, {Seok Jong} and Mingeol Lee and Kim, {Kwang Joong} and Ro, {Young Suck} and Song, {Hae Jun} and Shin, {Bong Seok} and Ahn, {Sung Ku} and Lee, {Ji Yeoun} and Won, {Young Ho} and Jang, {Min Soo} and Kim, {Ki Ho} and Kim, {Myung Hwa} and Kim, {Tae Yoon} and Choi, {Jee Ho}",
year = "2019",
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doi = "10.5021/ad.2019.31.1.29",
language = "English",
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pages = "29--36",
journal = "Annals of Dermatology",
issn = "1013-9087",
publisher = "Korean Dermatological Association",
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Choe, YB, Park, CJ, Yu, DY, Kim, Y, Ju, HJ, Youn, SW, Lee, JH, Kim, BS, Seo, SJ, Yun, SK, Park, J, Kim, NI, Youn, JI, Lee, SJ, Lee, M, Kim, KJ, Ro, YS, Song, HJ, Shin, BS, Ahn, SK, Lee, JY, Won, YH, Jang, MS, Kim, KH, Kim, MH, Kim, TY & Choi, JH 2019, 'Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis: Findings from the EPI-PSODE study', Annals of Dermatology, vol. 31, no. 1, pp. 29-36. https://doi.org/10.5021/ad.2019.31.1.29

Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis : Findings from the EPI-PSODE study. / Choe, Yong Beom; Park, Chul Jong; Yu, Dae Young; Kim, Youngdoe; Ju, Hyun Jeong; Youn, Sang Woong; Lee, Joo Heung; Kim, Byung Soo; Seo, Seong Jun; Yun, Seok Kweon; Park, Joonsoo; Kim, Nack In; Youn, Jai Il; Lee, Seok Jong; Lee, Mingeol; Kim, Kwang Joong; Ro, Young Suck; Song, Hae Jun; Shin, Bong Seok; Ahn, Sung Ku; Lee, Ji Yeoun; Won, Young Ho; Jang, Min Soo; Kim, Ki Ho; Kim, Myung Hwa; Kim, Tae Yoon; Choi, Jee Ho.

In: Annals of Dermatology, Vol. 31, No. 1, 01.02.2019, p. 29-36.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Usefulness of the psoriatic arthritis screening and evaluation questionnaire to monitor disease activity in management of patients with psoriasis

T2 - Findings from the EPI-PSODE study

AU - Choe, Yong Beom

AU - Park, Chul Jong

AU - Yu, Dae Young

AU - Kim, Youngdoe

AU - Ju, Hyun Jeong

AU - Youn, Sang Woong

AU - Lee, Joo Heung

AU - Kim, Byung Soo

AU - Seo, Seong Jun

AU - Yun, Seok Kweon

AU - Park, Joonsoo

AU - Kim, Nack In

AU - Youn, Jai Il

AU - Lee, Seok Jong

AU - Lee, Mingeol

AU - Kim, Kwang Joong

AU - Ro, Young Suck

AU - Song, Hae Jun

AU - Shin, Bong Seok

AU - Ahn, Sung Ku

AU - Lee, Ji Yeoun

AU - Won, Young Ho

AU - Jang, Min Soo

AU - Kim, Ki Ho

AU - Kim, Myung Hwa

AU - Kim, Tae Yoon

AU - Choi, Jee Ho

PY - 2019/2/1

Y1 - 2019/2/1

N2 - Background: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited. Objective: To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis. Methods: This was a multicenter, non-interventional, cross-sectional study. Demographic factors and PASI and PASE scores were collected to investigate associations between each. Results: PASE data were available for 1,255 patients, of whom 498 (39.7%) had a score of ≥37. Compared with the group with PASE score <37, the group with score ≥37 had a higher proportion of women (34.9% vs. 48.8%, p<0.0001), older mean age at diagnosis (36.4 vs. 41.7 years, p<0.0001), more severe disease activity using PASI and body surface area measures (p=0.0021 and p=0.0008, respectively), and higher mean body mass index (23.7 vs. 24.1, p=0.0411). In a multiple linear regression model, PASE score was positively associated with cutaneous disease activity (p<0.0001). Conclusion: After risk-adjustment, PASE was positively associated with PASI, which suggests that PASE can be sensitive to disease activity. Since psoriasis is regarded as one of the IMIDs, PASE may be utilized as a tool not only to screen PsA but also to monitor disease activity.

AB - Background: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis, such as the Psoriasis Area and Severity Index (PASI), are limited. Objective: To determine whether the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire can be used to monitor disease activity in patients with psoriasis. Methods: This was a multicenter, non-interventional, cross-sectional study. Demographic factors and PASI and PASE scores were collected to investigate associations between each. Results: PASE data were available for 1,255 patients, of whom 498 (39.7%) had a score of ≥37. Compared with the group with PASE score <37, the group with score ≥37 had a higher proportion of women (34.9% vs. 48.8%, p<0.0001), older mean age at diagnosis (36.4 vs. 41.7 years, p<0.0001), more severe disease activity using PASI and body surface area measures (p=0.0021 and p=0.0008, respectively), and higher mean body mass index (23.7 vs. 24.1, p=0.0411). In a multiple linear regression model, PASE score was positively associated with cutaneous disease activity (p<0.0001). Conclusion: After risk-adjustment, PASE was positively associated with PASI, which suggests that PASE can be sensitive to disease activity. Since psoriasis is regarded as one of the IMIDs, PASE may be utilized as a tool not only to screen PsA but also to monitor disease activity.

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JO - Annals of Dermatology

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