Utility of cardiac computed tomography for evaluation of pannus in mechanical aortic valve

Young Joo Suh, Young Jin Kim, Sak Lee, Yoo Jin Hong, Hye Jeong Lee, Jin Hur, Byoung Wook Choi, Byung Chul Chang

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The clinical significance of pannus detected on computed tomography (CT) has not yet been investigated. The purposes of this study were to investigate the clinical significance of pannus detected on cardiac CT in patients who underwent aortic valve replacement (AVR) with mechanical valves, and to determine predictors for pannus severity. A total of 92 patients who underwent cardiac CT and TTE and who had undergone mechanical AVR were included. The geometric orifice area (GOA), the presence of limitation of motion (LOM) and pannus were evaluated on CT. The GOA, presence of LOM, and presence and severity of pannus were compared with echocardiographic parameters. Logistic regression analysis was performed to determine the predictors for pannus severity. The GOA on CT positively correlated with effective orifice area on TTE (r = 0.733, P < 0.0001). Pannus was found in 77.2 % and LOM in 14.0 %. With increasing pannus severity, mean transvalvular pressure gradient (PG) was significantly higher (P < 0.0001). Patients with elevated PG showed a smaller GOA, a higher incidence of pannus, more severe pannus and LOM than patients with normal PG (P < 0.05). Small valve size (≤19 mm), Carbomedics valve, rheumatic etiology, and young age at AVR (<48.8 years) were independent predictors of moderate to severe pannus (P < 0.05). Cardiac CT is helpful in the evaluation of pannus formation in patients with mechanical aortic valves. Moderate to severe pannus formation frequently occurred in patients with small mechanical valve size, Carbomedics valves, rheumatic heart disease and young age at AVR.

Original languageEnglish
Pages (from-to)1271-1280
Number of pages10
JournalInternational Journal of Cardiovascular Imaging
Volume31
Issue number6
DOIs
Publication statusPublished - 2015 Aug 2

Fingerprint

Aortic Valve
Tomography
Pressure
Rheumatic Heart Disease
Logistic Models
Regression Analysis
Incidence

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Suh, Young Joo ; Kim, Young Jin ; Lee, Sak ; Hong, Yoo Jin ; Lee, Hye Jeong ; Hur, Jin ; Choi, Byoung Wook ; Chang, Byung Chul. / Utility of cardiac computed tomography for evaluation of pannus in mechanical aortic valve. In: International Journal of Cardiovascular Imaging. 2015 ; Vol. 31, No. 6. pp. 1271-1280.
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abstract = "The clinical significance of pannus detected on computed tomography (CT) has not yet been investigated. The purposes of this study were to investigate the clinical significance of pannus detected on cardiac CT in patients who underwent aortic valve replacement (AVR) with mechanical valves, and to determine predictors for pannus severity. A total of 92 patients who underwent cardiac CT and TTE and who had undergone mechanical AVR were included. The geometric orifice area (GOA), the presence of limitation of motion (LOM) and pannus were evaluated on CT. The GOA, presence of LOM, and presence and severity of pannus were compared with echocardiographic parameters. Logistic regression analysis was performed to determine the predictors for pannus severity. The GOA on CT positively correlated with effective orifice area on TTE (r = 0.733, P < 0.0001). Pannus was found in 77.2 {\%} and LOM in 14.0 {\%}. With increasing pannus severity, mean transvalvular pressure gradient (PG) was significantly higher (P < 0.0001). Patients with elevated PG showed a smaller GOA, a higher incidence of pannus, more severe pannus and LOM than patients with normal PG (P < 0.05). Small valve size (≤19 mm), Carbomedics valve, rheumatic etiology, and young age at AVR (<48.8 years) were independent predictors of moderate to severe pannus (P < 0.05). Cardiac CT is helpful in the evaluation of pannus formation in patients with mechanical aortic valves. Moderate to severe pannus formation frequently occurred in patients with small mechanical valve size, Carbomedics valves, rheumatic heart disease and young age at AVR.",
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Utility of cardiac computed tomography for evaluation of pannus in mechanical aortic valve. / Suh, Young Joo; Kim, Young Jin; Lee, Sak; Hong, Yoo Jin; Lee, Hye Jeong; Hur, Jin; Choi, Byoung Wook; Chang, Byung Chul.

In: International Journal of Cardiovascular Imaging, Vol. 31, No. 6, 02.08.2015, p. 1271-1280.

Research output: Contribution to journalArticle

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