Abstract
Background and Aims: It has been unclear as to whether the Rome II criteria could be applied to patients in the Asia region with functional gastrointestinal (GI) diseases. The aim of the present study was to determine if symptoms of Asian patients with functional gastrointestinal disorders formed groups which corresponded to the Rome II diagnostic criteria. Methods: A modified English version of Talley's bowel disease questionnaire was developed in collaboration with various research teams in accordance with the Rome II criteria. This instrument was translated into the local languages of the following nine Asian regions: China, Hong Kong, Indonesia, Korea, Malaysia, Singapore, Taiwan, Thailand and Vietnam. From September to December 2001, newly enrolled outpatients attending 14 GI or medical clinics in these regions were invited to complete the questionnaire. From these respondents, patients with functional gastrointestinal disorders fulfilling the '12 weeks out of 12 months' criteria were separated for further analysis. Principal component factor analysis with varimax rotation was used to identify symptom clusters or factors. These factors were compared with the existing classification of functional GI diseases derived from the Rome II criteria. Results: Factor analysis of symptoms from 1012 functional GI patients supported the Rome II classification of the following groups of functional GI disorders: diarrhea-predominant irritable bowel syndrome, functional constipation, functional dyspepsia, functional abdominal pain syndrome, functional heartburn, and functional vomiting. Functional diarrhea was combined with functional anorectal disorders, and globus merged with functional dysphagia into one factor. Some of the functional dyspepsia, abdominal bloating and belching symptoms were loaded into one factor. Conclusions: Factor analysis of symptoms from a sample of Asian patients with functional GI disorders partially supported the use of the Rome II classification.
| Original language | English |
|---|---|
| Pages (from-to) | 796-802 |
| Number of pages | 7 |
| Journal | Journal of Gastroenterology and Hepatology (Australia) |
| Volume | 18 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2003 Jul 1 |
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All Science Journal Classification (ASJC) codes
- Hepatology
- Gastroenterology
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Validation of Rome II criteria for functional gastrointestinal disorders by factor analysis of symptoms in Asian patient sample. / Kwan, Ambrose Chi Pong; Bao, Tran Ngoc; Chakkaphak, Suriya; Chang, Full Young; Ke, Mei Yun; Law, Ngai Moh; Leelakusolvong, Somchai; Luo, Jin Yan; Manan, Chudahman; Park, HyoJin; Piyaniran, Wanich; Qureshi, Akhtar; Long, Ta; Xu, Guo Ming; Xu, Liying; Yuen, Hon.
In: Journal of Gastroenterology and Hepatology (Australia), Vol. 18, No. 7, 01.07.2003, p. 796-802.Research output: Contribution to journal › Article
TY - JOUR
T1 - Validation of Rome II criteria for functional gastrointestinal disorders by factor analysis of symptoms in Asian patient sample
AU - Kwan, Ambrose Chi Pong
AU - Bao, Tran Ngoc
AU - Chakkaphak, Suriya
AU - Chang, Full Young
AU - Ke, Mei Yun
AU - Law, Ngai Moh
AU - Leelakusolvong, Somchai
AU - Luo, Jin Yan
AU - Manan, Chudahman
AU - Park, HyoJin
AU - Piyaniran, Wanich
AU - Qureshi, Akhtar
AU - Long, Ta
AU - Xu, Guo Ming
AU - Xu, Liying
AU - Yuen, Hon
PY - 2003/7/1
Y1 - 2003/7/1
N2 - Background and Aims: It has been unclear as to whether the Rome II criteria could be applied to patients in the Asia region with functional gastrointestinal (GI) diseases. The aim of the present study was to determine if symptoms of Asian patients with functional gastrointestinal disorders formed groups which corresponded to the Rome II diagnostic criteria. Methods: A modified English version of Talley's bowel disease questionnaire was developed in collaboration with various research teams in accordance with the Rome II criteria. This instrument was translated into the local languages of the following nine Asian regions: China, Hong Kong, Indonesia, Korea, Malaysia, Singapore, Taiwan, Thailand and Vietnam. From September to December 2001, newly enrolled outpatients attending 14 GI or medical clinics in these regions were invited to complete the questionnaire. From these respondents, patients with functional gastrointestinal disorders fulfilling the '12 weeks out of 12 months' criteria were separated for further analysis. Principal component factor analysis with varimax rotation was used to identify symptom clusters or factors. These factors were compared with the existing classification of functional GI diseases derived from the Rome II criteria. Results: Factor analysis of symptoms from 1012 functional GI patients supported the Rome II classification of the following groups of functional GI disorders: diarrhea-predominant irritable bowel syndrome, functional constipation, functional dyspepsia, functional abdominal pain syndrome, functional heartburn, and functional vomiting. Functional diarrhea was combined with functional anorectal disorders, and globus merged with functional dysphagia into one factor. Some of the functional dyspepsia, abdominal bloating and belching symptoms were loaded into one factor. Conclusions: Factor analysis of symptoms from a sample of Asian patients with functional GI disorders partially supported the use of the Rome II classification.
AB - Background and Aims: It has been unclear as to whether the Rome II criteria could be applied to patients in the Asia region with functional gastrointestinal (GI) diseases. The aim of the present study was to determine if symptoms of Asian patients with functional gastrointestinal disorders formed groups which corresponded to the Rome II diagnostic criteria. Methods: A modified English version of Talley's bowel disease questionnaire was developed in collaboration with various research teams in accordance with the Rome II criteria. This instrument was translated into the local languages of the following nine Asian regions: China, Hong Kong, Indonesia, Korea, Malaysia, Singapore, Taiwan, Thailand and Vietnam. From September to December 2001, newly enrolled outpatients attending 14 GI or medical clinics in these regions were invited to complete the questionnaire. From these respondents, patients with functional gastrointestinal disorders fulfilling the '12 weeks out of 12 months' criteria were separated for further analysis. Principal component factor analysis with varimax rotation was used to identify symptom clusters or factors. These factors were compared with the existing classification of functional GI diseases derived from the Rome II criteria. Results: Factor analysis of symptoms from 1012 functional GI patients supported the Rome II classification of the following groups of functional GI disorders: diarrhea-predominant irritable bowel syndrome, functional constipation, functional dyspepsia, functional abdominal pain syndrome, functional heartburn, and functional vomiting. Functional diarrhea was combined with functional anorectal disorders, and globus merged with functional dysphagia into one factor. Some of the functional dyspepsia, abdominal bloating and belching symptoms were loaded into one factor. Conclusions: Factor analysis of symptoms from a sample of Asian patients with functional GI disorders partially supported the use of the Rome II classification.
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UR - http://www.scopus.com/inward/citedby.url?scp=0042202162&partnerID=8YFLogxK
U2 - 10.1046/j.1440-1746.2003.03081.x
DO - 10.1046/j.1440-1746.2003.03081.x
M3 - Article
VL - 18
SP - 796
EP - 802
JO - Journal of Gastroenterology and Hepatology (Australia)
JF - Journal of Gastroenterology and Hepatology (Australia)
SN - 0815-9319
IS - 7
ER -