Validation of the Korean-version of the nonmotor symptoms scale for Parkinson's disease

Seong Beom Koh, Jae Woo Kim, Hyeo Il Ma, Tae Beom Ahn, Jin Whan Cho, Phil Hyu Lee, Sun Ju Chung, Joong Seok Kim, Do Young Kwon, Jong Sam Baik

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Abstract

Background and Purpose Non-motor symptoms are common in Parkinson's disease (PD), and are the primary cause of disability in many PD patients. Our aim in this study was to translate the origin non-motor symptoms scale for PD (NMSS), which was written in English, into Korean (K-NMSS), and to evaluate its reliability and validity for use with Korean-speaking patients with PD. Methods In total, 102 patients with PD from 9 movement disorders sections of university teaching hospitals in Korea were enrolled in this study. They were assessed using the K-NMSS, the Unified Parkinson's Disease Rating Scale (UPDRS), the Korean version of the Mini-Mental Status Examination (K-MMSE), the Korean version of the Montgomery-Asberg Depression Rating Scale (K-MADS), the Epworth Sleepiness Scale (ESS), and Parkinson's Disease Questionnaire 39 (PDQ39). Test-retest reliability was assessed over a time interval of 10-14 days in all but one patient. Results The K-NMSS was administered to 102 patients with PD. The internal consistency and reliability of this tool was 0.742 (mean Cronbach's α-coefficient). The test-retest correlation reliability was 0.941 (Guttman split-half coefficient). There was a moderate correlation between the total K-NMSS score and the scores for UPDRS part I [Spearman's rank correlation coefficient, (rS)=0.521, p<0.001] and UPDRS part II (rS=0.464, p=0.001), but there was only a weak correlation between the total K-NMSS score and the UPDRS part III score (rS=0.288, p=0.003). The total K-NMSS score was significantly correlated with the K-MADS (rS=0.594, p<0.001), K-MMSE (rS=-0.291, p=0.003), and ESS (rS=0.348, p<0.001). The total K-NMSS score was also significantly and positively correlated with the PDQ39 score (rS=0.814, p<0.001). Conclusions The K-NMSS exhibited good reliability and validity for the assessment of non-motor symptoms in Korean PD patients.

Original languageEnglish
Pages (from-to)276-283
Number of pages8
JournalJournal of Clinical Neurology (Korea)
Volume8
Issue number4
DOIs
Publication statusPublished - 2012 Dec 1

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All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Koh, S. B., Kim, J. W., Ma, H. I., Ahn, T. B., Cho, J. W., Lee, P. H., Chung, S. J., Kim, J. S., Kwon, D. Y., & Baik, J. S. (2012). Validation of the Korean-version of the nonmotor symptoms scale for Parkinson's disease. Journal of Clinical Neurology (Korea), 8(4), 276-283. https://doi.org/10.3988/jcn.2012.8.4.276