Validation of the modified 4-tiered categorization system through comparison with the 5-tiered categorization system of the 2015 American Thyroid Association guidelines for classifying small thyroid nodules on ultrasound

Ji Hye Lee, Kyunghwa Han, Eunkyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y. Park, jinyoung kwak

Research output: Contribution to journalArticle

Abstract

Background: The purpose of this study was to validate the modified 4-tiered categorization system and to compare stratification of malignancy risk in small thyroid nodules with the 2015 American Thyroid Association (ATA) management guidelines. Methods: From January 2015 to December 2015, 737 thyroid nodules measured ≥ 1 cm and <2 cm were included in this study. Each nodule was assigned a category with the ultrasonographic patterns described by the 2015 ATA guidelines. Results: On univariate analysis, there was no difference of malignancy risk between low suspicion and very low suspicion nodules (P =.584). Therefore, we suggested a modified 4-tiered categorization, which combines very low suspicion and low suspicion nodules into the “revised low suspicion” category. Specificity, positive predictive value (PPV) and accuracy were higher with the modified 4-tiered categorization system (P <.001 for all). Conclusion: The modified 4-tiered categorization system allows more efficient management with better diagnostic performance than the 2015 ATA categorization system in small thyroid nodules.

Original languageEnglish
Pages (from-to)2208-2215
Number of pages8
JournalHead and Neck
Volume39
Issue number11
DOIs
Publication statusPublished - 2017 Nov 1

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Thyroid Nodule
Guidelines
Thyroid Gland
Neoplasms

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

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title = "Validation of the modified 4-tiered categorization system through comparison with the 5-tiered categorization system of the 2015 American Thyroid Association guidelines for classifying small thyroid nodules on ultrasound",
abstract = "Background: The purpose of this study was to validate the modified 4-tiered categorization system and to compare stratification of malignancy risk in small thyroid nodules with the 2015 American Thyroid Association (ATA) management guidelines. Methods: From January 2015 to December 2015, 737 thyroid nodules measured ≥ 1 cm and <2 cm were included in this study. Each nodule was assigned a category with the ultrasonographic patterns described by the 2015 ATA guidelines. Results: On univariate analysis, there was no difference of malignancy risk between low suspicion and very low suspicion nodules (P =.584). Therefore, we suggested a modified 4-tiered categorization, which combines very low suspicion and low suspicion nodules into the “revised low suspicion” category. Specificity, positive predictive value (PPV) and accuracy were higher with the modified 4-tiered categorization system (P <.001 for all). Conclusion: The modified 4-tiered categorization system allows more efficient management with better diagnostic performance than the 2015 ATA categorization system in small thyroid nodules.",
author = "Lee, {Ji Hye} and Kyunghwa Han and Eunkyung Kim and Moon, {Hee Jung} and Yoon, {Jung Hyun} and Park, {Vivian Y.} and jinyoung kwak",
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Validation of the modified 4-tiered categorization system through comparison with the 5-tiered categorization system of the 2015 American Thyroid Association guidelines for classifying small thyroid nodules on ultrasound. / Lee, Ji Hye; Han, Kyunghwa; Kim, Eunkyung; Moon, Hee Jung; Yoon, Jung Hyun; Park, Vivian Y.; kwak, jinyoung.

In: Head and Neck, Vol. 39, No. 11, 01.11.2017, p. 2208-2215.

Research output: Contribution to journalArticle

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AU - Kim, Eunkyung

AU - Moon, Hee Jung

AU - Yoon, Jung Hyun

AU - Park, Vivian Y.

AU - kwak, jinyoung

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