Valorization of nano-based lignocellulosic derivatives to procure commercially significant value-added products for biomedical applications

Vickram AS, Gopalakrishnan Kumar, Nibedita Dey, Rohini Karunakaran, Anbarasu K, Anil Kumar Patel, Thanigaivel S, Gangadhar Andaluri, Yuan Chung Lin, Deena Santhana Raj, Vinoth Kumar Ponnusamy

Research output: Contribution to journalArticlepeer-review


Biowaste, produced from nature, is preferred to be a good source of carbon and ligninolytic machinery for many microorganisms. They are complex biopolymers composed of lignin, cellulose, and hemicellulose traces. This biomass can be depolymerized to its nano-dimensions to gain exceptional properties useful in the field of cosmetics, pharmaceuticals, high-strength materials, etc. Nano-sized biomass derivatives overcome the inherent drawbacks of the parent material and offer promises as a potential material for a wide range of applications with their unique traits such as low-toxicity, biocompatibility, biodegradability and environmentally friendly nature with versatility. This review focuses on the production of value–added products feasible from nanocellulose, nano lignin, and xylan nanoparticles which is quite a novel study of its kind. Dawn of nanotechnology has converted bio waste by–products (hemicellulose and lignin) into useful precursors for many commercial products. Nano-cellulose has been employed in the fields of electronics, cosmetics, drug delivery, scaffolds, fillers, packaging, and engineering structures. Xylan nanoparticles and nano lignin have numerous applications as stabilizers, additives, textiles, adhesives, emulsifiers, and prodrugs for many polyphenols with an encapsulation efficiency of 50%. This study will support the potential development of composites for emerging applications in all aspects of interest and open up novel paths for multifunctional biomaterials in nano-dimensions for cosmetic, drug carrier, and clinical applications.

Original languageEnglish
Article number114400
JournalEnvironmental Research
Publication statusPublished - 2023 Jan 1

Bibliographical note

Funding Information:
Authors thank the National Science and Technology Council, , Taiwan for a research grant NSTC-111-2113-M-037-012-Y1 . This work was supported partially by the Research Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan and by Kaohsiung Medical University Research Center Grant ( KMU-TC111A01 and KMUTC111IFSP01 ).

Publisher Copyright:
© 2022 Elsevier Inc.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Environmental Science(all)


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