Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery

Vivian Youngjean Park, Eunkyung Kim, Hee Jung Moon, Jung Hyun Yoon, minjung Kim

Research output: Contribution to journalArticle

Abstract

Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5%) obtained negative and 59 (25.5%) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6% [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3% (59/60), 100% (171/171), 100% (59/59) and 99.4% (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1% (51/52),100% (170/170),100% (51/51) and 99.4% (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.

Original languageEnglish
Pages (from-to)969-973
Number of pages5
JournalAmerican Journal of Surgery
Volume216
Issue number5
DOIs
Publication statusPublished - 2018 Nov 1

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Fine Needle Biopsy
Lymph Nodes
Breast Neoplasms
Recurrence
Ultrasonography
Sensitivity and Specificity
Cell Biology
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

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title = "Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery",
abstract = "Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5{\%}) obtained negative and 59 (25.5{\%}) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6{\%} [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3{\%} (59/60), 100{\%} (171/171), 100{\%} (59/59) and 99.4{\%} (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1{\%} (51/52),100{\%} (170/170),100{\%} (51/51) and 99.4{\%} (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.",
author = "Park, {Vivian Youngjean} and Eunkyung Kim and Moon, {Hee Jung} and Yoon, {Jung Hyun} and minjung Kim",
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Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery. / Park, Vivian Youngjean; Kim, Eunkyung; Moon, Hee Jung; Yoon, Jung Hyun; Kim, minjung.

In: American Journal of Surgery, Vol. 216, No. 5, 01.11.2018, p. 969-973.

Research output: Contribution to journalArticle

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T1 - Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery

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AU - Kim, minjung

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AB - Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5%) obtained negative and 59 (25.5%) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6% [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3% (59/60), 100% (171/171), 100% (59/59) and 99.4% (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1% (51/52),100% (170/170),100% (51/51) and 99.4% (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.

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