Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery

Vivian Youngjean Park, Eun Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Min Jung Kim

Research output: Contribution to journalArticle

Abstract

Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5%) obtained negative and 59 (25.5%) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6% [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3% (59/60), 100% (171/171), 100% (59/59) and 99.4% (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1% (51/52),100% (170/170),100% (51/51) and 99.4% (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.

Original languageEnglish
Pages (from-to)969-973
Number of pages5
JournalAmerican Journal of Surgery
Volume216
Issue number5
DOIs
Publication statusPublished - 2018 Nov

Fingerprint

Fine Needle Biopsy
Lymph Nodes
Breast Neoplasms
Recurrence
Ultrasonography
Sensitivity and Specificity
Cell Biology
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

@article{2f162350cb1f4879b5b32d5ab660ad34,
title = "Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery",
abstract = "Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5{\%}) obtained negative and 59 (25.5{\%}) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6{\%} [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3{\%} (59/60), 100{\%} (171/171), 100{\%} (59/59) and 99.4{\%} (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1{\%} (51/52),100{\%} (170/170),100{\%} (51/51) and 99.4{\%} (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.",
author = "Park, {Vivian Youngjean} and Kim, {Eun Kyung} and Moon, {Hee Jung} and Yoon, {Jung Hyun} and Kim, {Min Jung}",
year = "2018",
month = "11",
doi = "10.1016/j.amjsurg.2018.04.012",
language = "English",
volume = "216",
pages = "969--973",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "5",

}

Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery. / Park, Vivian Youngjean; Kim, Eun Kyung; Moon, Hee Jung; Yoon, Jung Hyun; Kim, Min Jung.

In: American Journal of Surgery, Vol. 216, No. 5, 11.2018, p. 969-973.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Value of ultrasound-guided fine needle aspiration in diagnosing axillary lymph node recurrence after breast cancer surgery

AU - Park, Vivian Youngjean

AU - Kim, Eun Kyung

AU - Moon, Hee Jung

AU - Yoon, Jung Hyun

AU - Kim, Min Jung

PY - 2018/11

Y1 - 2018/11

N2 - Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5%) obtained negative and 59 (25.5%) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6% [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3% (59/60), 100% (171/171), 100% (59/59) and 99.4% (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1% (51/52),100% (170/170),100% (51/51) and 99.4% (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.

AB - Background: This article aims to assess the diagnostic performance of ultrasound-guided fine needle aspiration (US-FNA) in diagnosing axillary lymph node (ALN) recurrence in patients with a history of breast cancer. Methods: From January 2005 to June 2015, 231 US-FNA examinations performed for suspicious axillary lesions in 218 patients with a history of breast cancer were included. Diagnostic performance of US-FNA for ALN recurrence were evaluated. Results: Of the 231 US-FNA examinations, 172 (74.5%) obtained negative and 59 (25.5%) obtained positive cytological results. All US-FNA-negative axillary lesions were considered imaging-cytology concordant and underwent follow-up, with one false-negative result (false negative rate, 1.6% [1/60]). The overall sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence/metastasis per examination were 98.3% (59/60), 100% (171/171), 100% (59/59) and 99.4% (171/172). When excluding nine patients with newly developed contralateral breast cancer, the sensitivity, specificity, PPV and NPV of US-FNA for diagnosing ALN recurrence was 98.1% (51/52),100% (170/170),100% (51/51) and 99.4% (170/171). Conclusions: US-FNA is a reliable method for diagnosing axillary recurrence in patients with a history of breast cancer.

UR - http://www.scopus.com/inward/record.url?scp=85055853824&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055853824&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2018.04.012

DO - 10.1016/j.amjsurg.2018.04.012

M3 - Article

C2 - 29709272

AN - SCOPUS:85055853824

VL - 216

SP - 969

EP - 973

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 5

ER -