Variability in Interpretation of Ultrasound Elastography and Gray-Scale Ultrasound in Assessing Thyroid Nodules

Jieun Koh, Hee Jung Moon, Jeong Seon Park, Soo Jin Kim, Ha Yan Kim, Eunkyung Kim, jinyoung kwak

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The aim of this study was to validate inter-observer variability for strain ultrasound elastography (USE) and to compare the diagnostic performance of a combination of gray-scale ultrasound (US) and USE with that of gray-scale US. Three observers from different institutions evaluated gray-scale US images and USE video files of 443 cytopathologically proven benign or malignant thyroid nodules over a 3-mo period. Inter-observer variability did not statistically differ between USE using the Asteria criteria and gray-scale US; however, USE using the Rago criteria had the lowest inter-observer agreement (p < 0.043). For all three observers, sensitivity was increased by adding USE to gray-scale US (81.3%–88.3%, 75.4%–85.4%) compared with gray-scale US (70.4%–80.8%). Specificity was decreased by adding USE to gray-scale US (51.7%–59.1%, 59.1%–73.9%) compared with gray-scale US (69.0%–82.8%). USE and gray-scale US had comparable inter-observer variability. However, on addition of USE to gray-scale US, the additional diagnostic yield was limited compared with that of gray-scale US alone.

Original languageEnglish
Pages (from-to)51-59
Number of pages9
JournalUltrasound in Medicine and Biology
Volume42
Issue number1
DOIs
Publication statusPublished - 2016 Jan 1

Fingerprint

Elasticity Imaging Techniques
Thyroid Nodule
nodules
gray scale
Observer Variation
Ultrasonography
files

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

Cite this

Koh, Jieun ; Moon, Hee Jung ; Park, Jeong Seon ; Kim, Soo Jin ; Kim, Ha Yan ; Kim, Eunkyung ; kwak, jinyoung. / Variability in Interpretation of Ultrasound Elastography and Gray-Scale Ultrasound in Assessing Thyroid Nodules. In: Ultrasound in Medicine and Biology. 2016 ; Vol. 42, No. 1. pp. 51-59.
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Variability in Interpretation of Ultrasound Elastography and Gray-Scale Ultrasound in Assessing Thyroid Nodules. / Koh, Jieun; Moon, Hee Jung; Park, Jeong Seon; Kim, Soo Jin; Kim, Ha Yan; Kim, Eunkyung; kwak, jinyoung.

In: Ultrasound in Medicine and Biology, Vol. 42, No. 1, 01.01.2016, p. 51-59.

Research output: Contribution to journalArticle

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