Vertebral Reconstruction with Customized 3-Dimensional−Printed Spine Implant Replacing Large Vertebral Defect with 3-Year Follow-up

Kyu Seon Chung, Dong Ah Shin, Keung Nyun Kim, Yoon Ha, Do Heum Yoon, Seong Yi

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Background: Destruction of the spine is a huge complication of infectious spondylitis and surgical intervention is required. However, vertebral defect is a major problem after surgical intervention and numerous methods have been researched to solve this problem. There are known methods that use variously designed, patient-customized 3-dimensional (3D)-printed implants in various medical fields. The use of 3D-printed implants has also been attempted in treating defects in the spine. We present a case of failure of expandable titanium cage fusion after infection, treated using a 3D-printed implant. Case Description: The patient had undergone reconstruction surgery with expandable titanium cage due to infectious spondylitis and needed reoperation owing to recurrence of infections and failure of bone fusion. The problem we faced in this operation was a large vertebral defect, for which we used a 3D-printed implant. After 3 years of follow-up, the implant and bone fusion were intact and infection or mechanical complications were not seen. Conclusions: A 3D-printed implant could be an acceptable and alternative treatment option for replacing a large vertebral defect.

Original languageEnglish
Pages (from-to)90-95
Number of pages6
JournalWorld Neurosurgery
Publication statusPublished - 2019 Jun

Bibliographical note

Funding Information:
Conflict of interest statement: This study was supported by a faculty research grant of Yonsei University College of Medicine for 2017 (6-2017-0067), the National Research Foundation of Korea (NRF) grant funded by the Korea government (NRF-2014M3A7B4051596), and the Technology Innovation Program funded by the Ministry of Trade, Industry & Energy , Korea (10062712, Development of spinal fusion implant and its manufacturing system; the functionality optimized, patient-customized in terms of bioactive materials to meet the clinical needs).

Publisher Copyright:
© 2019 Elsevier Inc.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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