Visible light-enhanced antibacterial and osteogenic functionality of Au and Pt nanoparticles deposited on TiO2 nanotubes

Kyoung Suk Moon, Eun Joo Choi, Ji Myung Bae, Young Bum Park, Seunghan Oh

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9 Citations (Scopus)

Abstract

This study aimed at evaluating the visible light mediated antimicrobial and osteogenic applications of noble metal, such as gold (Au) and platinum (Pt) coated titania (TiO2) nanotubes (NTs). In this study, the Au and Pt nanoparticles (NPs) were deposited on anodized 100 nm TiO2 NTs by ion plasma sputtering. The Au and Pt NPs were mainly deposited on the top surface layer of TiO2 NTs and showed light absorbance peaks around the 470 and 600 nm visible light region used in this study, as seen from the surface characterization. From the results of antibacterial activity test, Au and Pt NPs that were deposited on TiO2 NTs showed excellent antibacterial activity under 470 nm visible light irradiation due to the plasmonic photocatalysis based on the localized surface plasmon resonance effect of the Au and Pt NPs. In addition, alkaline phosphate activity test and quantitative real-time PCR assay of osteogenic related genes resulted that these NPs promoted the osteogenic functionality of human mesenchymal stem cells (hMSCs) under 600 nm visible light irradiation, because of the synergic effect of the photothermal scattering of noble metal nanoparticles and visible light low-level laser therapy (LLLT). Therefore, the combination of noble metal coated TiO2 NTs and visible light irradiation would be expected to perform permanent antibacterial activity without the need of an antibacterial agent besides promoting osteogenic functionality.

Original languageEnglish
Article number3721
JournalMaterials
Volume13
Issue number17
DOIs
Publication statusPublished - 2020 Sep

Bibliographical note

Funding Information:
Funding: This work was supported by the National Research Foundation of Korea (NRF) (Grant No. 2019R1A2C1003249) which is funded by the Korea government (MSIT).

Publisher Copyright:
© 2020 by the authors.

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics

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