Vitiligo in children and adolescents: Association with thyroid dysfunction

S. B. Cho, J. H. Kim, S. Cho, J. M. Park, Y. K. Park, S. H. Oh

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background The clinical characteristics of vitiligo in children and adolescents with an emphasis on thyroid dysfunction have only been reported in a few studies. Objective The purpose of this study was to examine the characteristics of children and adolescents with vitiligo and compare the incidence of thyroid dysfunction between them and controls without vitiligo at the same age. Methods A retrospective analysis of 324 Korean children and adolescents with vitiligo was performed. The results of thyroid function screening tests in them (n = 254) were compared with controls (n = 122). Results Of the total 324 children and adolescents with vitiligo, vitiligo vulgaris was the most common type (42.3%) and the most commonly involved site was the face (54.6%). A total of 15 of 254 (5.9%) patients screened for thyroid function were diagnosed with thyroid disease (four had Hashimoto's thyroiditis; two, Graves' disease; seven, subclinical hypothyroidism; and two, subclinical hyperthyroidism). None of the 50 patients with segmental vitiligo showed any thyroid dysfunction (P = 0.047). There was no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group, in which seven of 122 (5.7%) showed thyroid dysfunction. Conclusion In this study, we demonstrated the characteristics of children and adolescents with vitiligo and also observed no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group.

Original languageEnglish
Pages (from-to)64-67
Number of pages4
JournalJournal of the European Academy of Dermatology and Venereology
Volume25
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

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Vitiligo
Thyroid Gland
Thyroid Diseases
Incidence
Thyroid Function Tests
Hashimoto Disease
Control Groups
Graves Disease
Hyperthyroidism
Hypothyroidism

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

Cite this

Cho, S. B. ; Kim, J. H. ; Cho, S. ; Park, J. M. ; Park, Y. K. ; Oh, S. H. / Vitiligo in children and adolescents : Association with thyroid dysfunction. In: Journal of the European Academy of Dermatology and Venereology. 2011 ; Vol. 25, No. 1. pp. 64-67.
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abstract = "Background The clinical characteristics of vitiligo in children and adolescents with an emphasis on thyroid dysfunction have only been reported in a few studies. Objective The purpose of this study was to examine the characteristics of children and adolescents with vitiligo and compare the incidence of thyroid dysfunction between them and controls without vitiligo at the same age. Methods A retrospective analysis of 324 Korean children and adolescents with vitiligo was performed. The results of thyroid function screening tests in them (n = 254) were compared with controls (n = 122). Results Of the total 324 children and adolescents with vitiligo, vitiligo vulgaris was the most common type (42.3{\%}) and the most commonly involved site was the face (54.6{\%}). A total of 15 of 254 (5.9{\%}) patients screened for thyroid function were diagnosed with thyroid disease (four had Hashimoto's thyroiditis; two, Graves' disease; seven, subclinical hypothyroidism; and two, subclinical hyperthyroidism). None of the 50 patients with segmental vitiligo showed any thyroid dysfunction (P = 0.047). There was no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group, in which seven of 122 (5.7{\%}) showed thyroid dysfunction. Conclusion In this study, we demonstrated the characteristics of children and adolescents with vitiligo and also observed no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group.",
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Vitiligo in children and adolescents : Association with thyroid dysfunction. / Cho, S. B.; Kim, J. H.; Cho, S.; Park, J. M.; Park, Y. K.; Oh, S. H.

In: Journal of the European Academy of Dermatology and Venereology, Vol. 25, No. 1, 01.01.2011, p. 64-67.

Research output: Contribution to journalArticle

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AB - Background The clinical characteristics of vitiligo in children and adolescents with an emphasis on thyroid dysfunction have only been reported in a few studies. Objective The purpose of this study was to examine the characteristics of children and adolescents with vitiligo and compare the incidence of thyroid dysfunction between them and controls without vitiligo at the same age. Methods A retrospective analysis of 324 Korean children and adolescents with vitiligo was performed. The results of thyroid function screening tests in them (n = 254) were compared with controls (n = 122). Results Of the total 324 children and adolescents with vitiligo, vitiligo vulgaris was the most common type (42.3%) and the most commonly involved site was the face (54.6%). A total of 15 of 254 (5.9%) patients screened for thyroid function were diagnosed with thyroid disease (four had Hashimoto's thyroiditis; two, Graves' disease; seven, subclinical hypothyroidism; and two, subclinical hyperthyroidism). None of the 50 patients with segmental vitiligo showed any thyroid dysfunction (P = 0.047). There was no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group, in which seven of 122 (5.7%) showed thyroid dysfunction. Conclusion In this study, we demonstrated the characteristics of children and adolescents with vitiligo and also observed no significant difference in the incidence of thyroid disease between children and adolescents with vitiligo and the control group.

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