Wearable microfluidics: fabric-based digital droplet flowmetry for perspiration analysis

Yahui Yang, Siyuan Xing, Zecong Fang, Ruya Li, Helen Koo, Tingrui Pan

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

The latest development in wearable technologies has attracted much attention. In particular, collection and analysis of body fluids has been a focus. In this paper, we have reported a wearable microfluidic platform made using conventional fabric materials and laser micromachining to measure the flow rate on a patterned fabric surface, referred to as digital droplet flowmetry (DDF). The proposed wearable DDF is capable of collecting and measuring continuous perspiration with high precision (96% on average) in a real-time fashion over a defined area of skin. We have introduced a theoretical model for the proposed wearable interfacial microfluidic platform, under which various design parameters have been investigated and optimized for various conditions. The novel digitalized measurement principle of DDF provides fast responses, digital readouts, system flexibility, and continuous performance of the flow measurement. Moreover, the proposed DDF platform can be conveniently implemented on regular apparel or a wearable device, and has potential to be applied to dynamic removal, collection and monitoring of biofluids for various physiological and clinical processes.

Original languageEnglish
Pages (from-to)926-935
Number of pages10
JournalLab on a chip
Volume17
Issue number5
DOIs
Publication statusPublished - 2017 Mar 7

Bibliographical note

Funding Information:
This work has been in part supported by the National Science Foundation Award (#DBI-1256193) and National Institute of Health Award (#1R21CA173243-01A1) granted to TP. The authors would like to thank Dr. Yingchu Wang for her help in the fabrication of the DDF prototypes.

Publisher Copyright:
© The Royal Society of Chemistry.

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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