Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association

Jongheon Shin, Jung Rae Rho, Youngwan Seo, Hyi Seung Lee, Ki Woong Cho, Ho Jeong Kwon, Chung J. Sim

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Wondonins A and B, two alkaloids of an unprecedented structural class, along with the previously described dihydroxystyryl sulfates, have been isolated from an association of the sponges Poecillastra wondoensis and Jaspis sp. collected from Keomun Island, Korea. The structures of these compounds have been determined as imidazole alkaloids containing a bis(dihydroxystyrene) moiety by combined spectroscopic methods. The new compounds exhibited antiangiogenic activity against human umbilical vein endothelial cells.

Original languageEnglish
Pages (from-to)1965-1968
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number10
DOIs
Publication statusPublished - 2001 Mar 4

Fingerprint

Imidazoles
Porifera
Alkaloids
Endothelial cells
Human Umbilical Vein Endothelial Cells
Korea
Islands
Sulfates
imidazole

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Shin, Jongheon ; Rho, Jung Rae ; Seo, Youngwan ; Lee, Hyi Seung ; Cho, Ki Woong ; Kwon, Ho Jeong ; Sim, Chung J. / Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 10. pp. 1965-1968.
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Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association. / Shin, Jongheon; Rho, Jung Rae; Seo, Youngwan; Lee, Hyi Seung; Cho, Ki Woong; Kwon, Ho Jeong; Sim, Chung J.

In: Tetrahedron Letters, Vol. 42, No. 10, 04.03.2001, p. 1965-1968.

Research output: Contribution to journalArticle

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AU - Shin, Jongheon

AU - Rho, Jung Rae

AU - Seo, Youngwan

AU - Lee, Hyi Seung

AU - Cho, Ki Woong

AU - Kwon, Ho Jeong

AU - Sim, Chung J.

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