Abstract
Background and Purpose: The hospital-based stroke registry is a well-established method useful for understanding diverse clinical characteristics of stroke related to geographical, racial or environmental differences. We analyzed the data from 1,000 patients with acute cerebral infarctions registered with the Yonsei Stroke Registry (YSR) which is the first prospective hospital-based observational study in Korea. Methods: All patients had cerebral infarctions and presented within 7 days of onset. CT or MRI was performed in all patients and a vascular imaging study (digital subtraction or magnetic resonance angiography) was conducted in 53.9% of the patients. Subtype classification was made through a consensus approach based on the strict application of TOAST criteria. Results: The mean age of patients was 62 ± 12 years, and 60.8% were males. Undetermined cause (UD) was the most frequent subtype (40.6%), which was followed by lacunar stroke (LS 21.5%), cardiac embolism (CE 18.3%), large-artery atherosclerosis (LAA 16.5%) and other determined causes (3.1%). Hypertension was found in 64.3%, smoking in 35.2%, diabetes mellitus in 26.9%, hypercholesterolemia in 24.1%, high hematocrit (≥50%) in 21.8%, clinically identified potential cardiac sources of embolism in 18.3%, a history of previous stroke in 22.0% and a history of previous transient ischemic attack in 4.7%. Recurrent stroke was associated with a higher number of risk factors (p < 0.001) and a higher incidence of LAA (p =0.003) than the first stroke. Vertebrobasilar artery territorial infarction was found in 39.8%, which was associated with higher incidences of LAA and LS and a lower incidence of CE than carotid artery territorial lesions (p =0.001). The 30-day mortality rate was 5.3% and cerebral herniation caused early death in 52%. Conclusion: The distribution of stroke subtypes in the YSR was largely comparable with that of western registries. The highest incidence of UD might be related to the strict application of TOAST criteria.
| Original language | English |
|---|---|
| Pages (from-to) | 145-151 |
| Number of pages | 7 |
| Journal | Cerebrovascular Diseases |
| Volume | 12 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2001 Oct 27 |
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All Science Journal Classification (ASJC) codes
- Neurology
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
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Yonsei Stroke Registry : Analysis of 1,000 patients with acute cerebral infarctions. / Lee, Byung In; Nam, Hyo Suk; Heo, Ji Hoe; Kim, Dong Ik; Shon, Young Ho; Kim, Seung Min; Park, Soo Chul; Kim, Jin Soo; Choi, Il Sang; Sunwoo, Il Nam; Kim, Gyung Whan; Choi, Chul Hee; Lee, Pil Hyu; Choi, Sun Ah; Park, Dong Chul; Lee, Kyung Yul; Han, Sang Won; Kim, Kyu Sik; Suh, Bum Cheon; Chung, Yun Kyung; Yoon, Pyung Ho; Chun, Jin Ill.
In: Cerebrovascular Diseases, Vol. 12, No. 3, 27.10.2001, p. 145-151.Research output: Contribution to journal › Article
TY - JOUR
T1 - Yonsei Stroke Registry
T2 - Analysis of 1,000 patients with acute cerebral infarctions
AU - Lee, Byung In
AU - Nam, Hyo Suk
AU - Heo, Ji Hoe
AU - Kim, Dong Ik
AU - Shon, Young Ho
AU - Kim, Seung Min
AU - Park, Soo Chul
AU - Kim, Jin Soo
AU - Choi, Il Sang
AU - Sunwoo, Il Nam
AU - Kim, Gyung Whan
AU - Choi, Chul Hee
AU - Lee, Pil Hyu
AU - Choi, Sun Ah
AU - Park, Dong Chul
AU - Lee, Kyung Yul
AU - Han, Sang Won
AU - Kim, Kyu Sik
AU - Suh, Bum Cheon
AU - Chung, Yun Kyung
AU - Yoon, Pyung Ho
AU - Chun, Jin Ill
PY - 2001/10/27
Y1 - 2001/10/27
N2 - Background and Purpose: The hospital-based stroke registry is a well-established method useful for understanding diverse clinical characteristics of stroke related to geographical, racial or environmental differences. We analyzed the data from 1,000 patients with acute cerebral infarctions registered with the Yonsei Stroke Registry (YSR) which is the first prospective hospital-based observational study in Korea. Methods: All patients had cerebral infarctions and presented within 7 days of onset. CT or MRI was performed in all patients and a vascular imaging study (digital subtraction or magnetic resonance angiography) was conducted in 53.9% of the patients. Subtype classification was made through a consensus approach based on the strict application of TOAST criteria. Results: The mean age of patients was 62 ± 12 years, and 60.8% were males. Undetermined cause (UD) was the most frequent subtype (40.6%), which was followed by lacunar stroke (LS 21.5%), cardiac embolism (CE 18.3%), large-artery atherosclerosis (LAA 16.5%) and other determined causes (3.1%). Hypertension was found in 64.3%, smoking in 35.2%, diabetes mellitus in 26.9%, hypercholesterolemia in 24.1%, high hematocrit (≥50%) in 21.8%, clinically identified potential cardiac sources of embolism in 18.3%, a history of previous stroke in 22.0% and a history of previous transient ischemic attack in 4.7%. Recurrent stroke was associated with a higher number of risk factors (p < 0.001) and a higher incidence of LAA (p =0.003) than the first stroke. Vertebrobasilar artery territorial infarction was found in 39.8%, which was associated with higher incidences of LAA and LS and a lower incidence of CE than carotid artery territorial lesions (p =0.001). The 30-day mortality rate was 5.3% and cerebral herniation caused early death in 52%. Conclusion: The distribution of stroke subtypes in the YSR was largely comparable with that of western registries. The highest incidence of UD might be related to the strict application of TOAST criteria.
AB - Background and Purpose: The hospital-based stroke registry is a well-established method useful for understanding diverse clinical characteristics of stroke related to geographical, racial or environmental differences. We analyzed the data from 1,000 patients with acute cerebral infarctions registered with the Yonsei Stroke Registry (YSR) which is the first prospective hospital-based observational study in Korea. Methods: All patients had cerebral infarctions and presented within 7 days of onset. CT or MRI was performed in all patients and a vascular imaging study (digital subtraction or magnetic resonance angiography) was conducted in 53.9% of the patients. Subtype classification was made through a consensus approach based on the strict application of TOAST criteria. Results: The mean age of patients was 62 ± 12 years, and 60.8% were males. Undetermined cause (UD) was the most frequent subtype (40.6%), which was followed by lacunar stroke (LS 21.5%), cardiac embolism (CE 18.3%), large-artery atherosclerosis (LAA 16.5%) and other determined causes (3.1%). Hypertension was found in 64.3%, smoking in 35.2%, diabetes mellitus in 26.9%, hypercholesterolemia in 24.1%, high hematocrit (≥50%) in 21.8%, clinically identified potential cardiac sources of embolism in 18.3%, a history of previous stroke in 22.0% and a history of previous transient ischemic attack in 4.7%. Recurrent stroke was associated with a higher number of risk factors (p < 0.001) and a higher incidence of LAA (p =0.003) than the first stroke. Vertebrobasilar artery territorial infarction was found in 39.8%, which was associated with higher incidences of LAA and LS and a lower incidence of CE than carotid artery territorial lesions (p =0.001). The 30-day mortality rate was 5.3% and cerebral herniation caused early death in 52%. Conclusion: The distribution of stroke subtypes in the YSR was largely comparable with that of western registries. The highest incidence of UD might be related to the strict application of TOAST criteria.
UR - http://www.scopus.com/inward/record.url?scp=0034769683&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034769683&partnerID=8YFLogxK
U2 - 10.1159/000047697
DO - 10.1159/000047697
M3 - Article
C2 - 11641577
AN - SCOPUS:0034769683
VL - 12
SP - 145
EP - 151
JO - Cerebrovascular Diseases
JF - Cerebrovascular Diseases
SN - 1015-9770
IS - 3
ER -